SCHEMBL5449016

SCHEMBL5449016

O=C(Cc1ccc(F)cc1)Nc1ccc2[nH]c3c(c2c1)CCCC3NC1CCCCC1

nearest known ligand 0.51

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
BRD3 Q15059 13/20 0.51
RB1 P06400 4/20 0.51
NMT2 O60551 1/20 0.50
NMT1 P30419 1/20 0.50
GAA P10253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5468005 0.91 RB1 (0.51) BRD3RB1NMT2NMT1GAA
SCHEMBL5475990 0.90 RB1 (0.54) BRD3RB1
SCHEMBL5456655 0.85 RB1 (0.56) BRD3RB1GAA
SCHEMBL5451546 0.84 RB1 (0.55) BRD3RB1GAA
SCHEMBL5468135 0.84 RB1 (0.55) BRD3RB1GAA
SCHEMBL5456607 0.82 GAA (0.49) BRD3RB1GAA
SCHEMBL5452796 0.82 RB1 (0.56) BRD3RB1GAA
SCHEMBL5466568 0.81 RB1 (0.58) BRD3RB1
SCHEMBL5460471 0.81 RB1 (0.58) BRD3RB1GAA
SCHEMBL5455563 0.81 RB1 (0.57) BRD3RB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070276009-A1 Compositions and Methods for Viral Inhibition CHIRON CORPORATION 2007-11-29 US disclosed
US-20070276009-A1 Compositions and Methods for Viral Inhibition CHIRON CORPORATION 2007-11-29 US disclosed
US-20070276009-A1 Compositions and Methods for Viral Inhibition CHIRON CORPORATION 2007-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070276009-A1 Compositions and Methods for Viral Inhibition MAVS, SARS1, ZC3HAV1 BRD3 529/4885RB1 1821/4885NMT2 3497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.