Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 16/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.35 |
| ▸ | CD38 | P28907 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5436749 | 0.88 | CYP19A1 (0.42) | CYP19A1STSCYP11B1CYP11B2 | |
| SCHEMBL5447325 | 0.76 | CYP19A1 (0.53) | CYP19A1STSCYP11B1CYP11B2 | |
| SCHEMBL5441196 | 0.72 | CYP19A1 (0.46) | CYP19A1STSCYP11B1CYP11B2CD38 | |
| SCHEMBL5439431 | 0.68 | CYP19A1 (0.46) | CYP19A1STSCYP11B1CYP11B2 | |
| SCHEMBL5440775 | 0.65 | CLK1 (0.39) | CYP19A1STSCD38 | |
| SCHEMBL5994566 | 0.65 | CYP19A1 (0.51) | CYP19A1STSCYP11B1CYP11B2 | |
| SCHEMBL5435430 | 0.65 | CYP19A1 (0.73) | CYP19A1STS | |
| SCHEMBL5474421 | 0.64 | CD38 (0.46) | CYP19A1CYP11B1CYP11B2CD38ALDH1A1 | |
| SCHEMBL5991945 | 0.64 | CYP19A1 (0.68) | CYP19A1STSCYP11B1CYP11B2 | |
| SCHEMBL5994547 | 0.64 | CYP19A1 (0.63) | CYP19A1STSCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476455-B2 | 1-N-phenyl-amino-1h-imidazole derivatives and pharmaceutical compositions containing them | LABORATOIRE THERAMEX (MC) | 2013-07-02 | — | — | US | disclosed |
| US-20070112009-A1 | 1-N-phenyl-amino-1h-imidazole derivatives and pharmaceutical compositions containing them | LABORATOIRE THERAMEX (MC) | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112009-A1 | 1-N-phenyl-amino-1h-imidazole derivatives and pharmaceutical compositions containing them | H1-0, H1-5, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | CYP19A1 761/4885STS 4396/4885CYP11B1 338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.