SCHEMBL544952

SCHEMBL544952

CCCCc1nc2c(N)nc3ccccc3c2n1CCCS(C)(=O)=O

nearest known ligand 0.75

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.75
TLR8 Q9NR97 3/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29374474 1.00 TLR7 (0.75) TLR7TLR8
SCHEMBL5360565 0.97 TLR7 (0.77) TLR7TLR8
SCHEMBL31006040 0.96 TLR7 (0.76) TLR7TLR8
SCHEMBL483645 0.96 TLR7 (0.76) TLR7TLR8
SCHEMBL5354224 0.95 TLR7 (0.74) TLR7TLR8
SCHEMBL29182349 0.95 TLR7 (0.67) TLR7TLR8
SCHEMBL5354054 0.93 TLR7 (0.71) TLR7TLR8
SCHEMBL5358579 0.92 TLR7 (0.69) TLR7TLR8
SCHEMBL5356930 0.91 TLR7 (0.71) TLR7TLR8
SCHEMBL5353504 0.91 TLR7 (0.67) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 259 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230390410-A1 COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY BIRDIE BIOPHARMACEUTICALS INC (KY) 2023-12-07 US claimed
US-11702476-B2 Anti-EGFR combinations for treating tumors BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2023-07-18 US claimed
US-11633494-B2 Compounds and compositions for immunotherapy BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2023-04-25 US claimed
EP-4148069-A1 ANTI-PD-L1 CONJUGATES FOR TREATING TUMORS Birdie Biopharmaceuticals Inc. (KY) 2023-03-15 EP claimed
CN-115554406-A anti-CD 20 combinations for the treatment of tumors 博笛生物科技有限公司 2023-01-03 CN claimed
CN-115350279-A anti-HER 2 combinations for the treatment of tumors 博笛生物科技有限公司 2022-11-18 CN claimed
CN-115337402-A Combination therapeutic compositions and combination therapeutic methods for treating cancer 博笛生物科技有限公司 2022-11-15 CN claimed
CN-115252792-A anti-EGFR combinations for the treatment of tumors 博笛生物科技有限公司 2022-11-01 CN claimed
EP-3763742-B1 ANTI-PD-L1 CONJUGATES FOR TREATING TUMORS BIRDIE BIOPHARMACEUTICALS INC (KY) 2022-10-05 EP claimed
EP-4056594-A1 COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY Birdie Biopharmaceuticals Inc. (KY) 2022-09-14 EP claimed
US-20170028079-A1 Compounds and Compositions for Treating HER2 Positive Tumors SHANGHAI BIRDIE BIOTECH, INC. (CN) 2017-02-02 US claimed
US-20160375148-A1 Compounds and Compositions for Treating EGFR Expressing Tumors BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2016-12-29 US claimed
US-20160324983-A1 Compounds and Compositions for Immunotherapy SHANGHAI BIRDIE BIOTECH, INC. (CN) 2016-11-10 US claimed
EP-1541572-A1 Thioether substituted imidazoquinolines 3M Innovative Properties Company (US) 2005-06-15 EP claimed
EP-1341791-B1 THIOETHER SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES CO (US) 2005-05-25 EP claimed
US-20040102471-A1 Thioether substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY 2004-05-27 US claimed
US-20040097736-A1 Thioether substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY 2004-05-20 US claimed
US-6664264-B2 Thioether substituted imidazoquinoline or tetrahydroimdazoquinoline compounds induce the biosynthesis of cytokines such as interferon and useful for treating viral disease in an animal 3M INNOVATIVE PROPERTIES COMPANY 2003-12-16 US claimed
US-20030100764-A1 Thioether substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY 2003-05-29 US claimed
US-20020173655-A1 Thioether substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY 2002-11-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11633494-B2 Compounds and compositions for immunotherapy CD47, CD274, TP53 TLR7 147/4885TLR8 313/4885
US-20170028079-A1 Compounds and Compositions for Treating HER2 Positive Tumors ERBB2, EGFR, TP53 TLR7 362/4885TLR8 249/4885
US-11702476-B2 Anti-EGFR combinations for treating tumors EGFR, ERBB3, ERBB2 TLR7 2007/4885TLR8 1153/4885
US-20160324983-A1 Compounds and Compositions for Immunotherapy CD47, TP53, CD74 TLR7 198/4885TLR8 159/4885
US-20160375148-A1 Compounds and Compositions for Treating EGFR Expressing Tumors EGFR, ERBB2, ERBB3 TLR7 634/4885TLR8 518/4885
US-20040097736-A1 Thioether substituted imidazoquinolines IFNG, IRF3, IL2 TLR7 30/4885TLR8 107/4885
US-20020173655-A1 Thioether substituted imidazoquinolines IFNG, IRF3, IL2 TLR7 30/4885TLR8 107/4885
US-20040102471-A1 Thioether substituted imidazoquinolines IFNG, IRF3, IL2 TLR7 30/4885TLR8 107/4885
US-20030100764-A1 Thioether substituted imidazoquinolines IFNG, IRF3, IL2 TLR7 30/4885TLR8 107/4885
US-20230390410-A1 COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY CD47, CD274, TP53 TLR7 147/4885TLR8 313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.