SCHEMBL5449665

SCHEMBL5449665

O=P(S)(OCc1ccccc1)SCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
CETP P11597 3/20 0.41
SRC P12931 1/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38
CA12 O43570 1/20 0.38
CA4 P22748 1/20 0.38
CA5A P35218 1/20 0.38
CA7 P43166 1/20 0.38
CA5B Q9Y2D0 1/20 0.38
PDPK1 O15530 1/20 0.37
MTOR P42345 1/20 0.37
ALPG P10696 1/20 0.37
PTK2B Q14289 1/20 0.37
IDO1 P14902 1/20 0.36
FOLH1 Q04609 1/20 0.36
HPGD P15428 1/20 0.36
AGXT P21549 1/20 0.35
ALDH1A1 P00352 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132691 0.98 TSHR (0.50) TSHRCETPSRCCA1CA2
SCHEMBL17315644 0.81 TSHR (0.55) TSHRCETPSRCCA1CA2
SCHEMBL18279944 0.81 TSHR (0.55) TSHRCETPSRCCA1CA2
SCHEMBL7888682 0.80 HPGD (0.41) TSHRCA1CA2CA9CA12
SCHEMBL3084433 0.79 TSHR (0.49) TSHRCETPSRCCA1CA2
SCHEMBL8469027 0.79 TSHR (0.61) TSHRCETPSRCPDPK1MTOR
SCHEMBL3072265 0.79 TSHR (0.43) TSHRCETPSRCCA1CA2
SCHEMBL3067247 0.77 TSHR (0.42) TSHRSRCCA1CA2CA9
SCHEMBL7074455 0.77 HPGD (0.43) TSHRCA1CA2CA9CA12
SCHEMBL6830707 0.77 HPGD (0.43) TSHRCA1CA2CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3434756-B1 LUBRICANT OIL COMPOSITION AND LUBRICATION METHOD IDEMITSU KOSAN CO (JP) 2022-10-05 EP disclosed
CN-107532106-B Lubricating oil composition 出光兴产株式会社 2021-10-08 CN disclosed
US-11124732-B2 Lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2021-09-21 US disclosed
CN-105164238-B Lubricating oil composition 出光兴产株式会社 2021-06-29 CN disclosed
US-10883064-B2 Lubricant oil composition and lubrication method IDEMITSU KOSAN CO., LTD. (JP) 2021-01-05 US disclosed
EP-2980194-B1 LUBRICANT OIL COMPOSITION IDEMITSU KOSAN CO (JP) 2020-04-01 EP disclosed
US-10563148-B2 Lubricant oil composition IDEMITSU KOSAN CO., LTD. (JP) 2020-02-18 US disclosed
US-10336859-B2 Method for preparing an electrolyte capacitor TAYCA CORPORATION (JP) 2019-07-02 US disclosed
US-20190119597-A1 LUBRICANT OIL COMPOSITION AND LUBRICATION METHOD IDEMITSU KOSAN CO., LTD. (JP) 2019-04-25 US disclosed
US-20190106531-A1 Method for preparing an electrolyte capacitor TAYCA CORPORATION (JP) 2019-04-11 US disclosed
US-9410106-B2 Lubricating oil composition IDEMITSU KOSAN CO., LTD. (JP) 2016-08-09 US disclosed
US-20160032214-A1 LUBRICANT OIL COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2016-02-04 US disclosed
EP-2980194-A1 LUBRICANT OIL COMPOSITION Idemitsu Kosan Co., Ltd (JP) 2016-02-03 EP disclosed
US-20150051128-A1 LUBRICATING OIL COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2015-02-19 US disclosed
EP-2826847-A1 LUBRICATING OIL COMPOSITION Idemitsu Kosan Co., Ltd (JP) 2015-01-21 EP disclosed
US-20070042918-A1 Lubricating oil additive and lubricating oil composition IDEMITSU KOSAN CO., LTD. (JP) 2007-02-22 US disclosed
US-5942470-A OIL SOLUBLE SULFUR CONTAINING PRESSURE AND ANTI-WEAR AGENT, AMINE SALT OF PHOSPHORUS ESTER, SUCCINIMIDE, AND ASHLESS DISPERSANTS ETHYL PETROLEUM ADDITIVES, INC. (US) 1999-08-24 US disclosed
EP-0459656-B1 Lubricant compositions ETHYL PETROLEUM ADDITIVES INC (US) 1995-09-20 EP disclosed
EP-0459656-A1 Lubricant compositions ETHYL PETROLEUM ADDITIVES, INC. (US) 1991-12-04 EP disclosed
US-4115482-A PESTICIDES EXXON RESEARCH AND ENGINEERING COMPANY (US) 1978-09-19 US disclosed