SCHEMBL132691

SCHEMBL132691

O=P(S)(OCc1ccccc1)SCc1ccccc1.[Zn]

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
CETP P11597 3/20 0.40
SRC P12931 1/20 0.37
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA9 Q16790 2/20 0.37
CA12 O43570 1/20 0.37
CA4 P22748 1/20 0.37
CA5A P35218 1/20 0.37
CA7 P43166 1/20 0.37
CA5B Q9Y2D0 1/20 0.37
PDPK1 O15530 1/20 0.36
MTOR P42345 1/20 0.36
ALPG P10696 1/20 0.36
PTK2B Q14289 1/20 0.36
FOLH1 Q04609 1/20 0.35
IDO1 P14902 1/20 0.35
HPGD P15428 1/20 0.35
AGXT P21549 1/20 0.34
ALDH1A1 P00352 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5449665 0.98 TSHR (0.52) TSHRCETPSRCCA1CA2
SCHEMBL18279944 0.80 TSHR (0.55) TSHRCETPSRCCA1CA2
SCHEMBL17315644 0.80 TSHR (0.55) TSHRCETPSRCCA1CA2
SCHEMBL7888682 0.79 HPGD (0.41) TSHRCA1CA2CA9CA12
SCHEMBL3084433 0.78 TSHR (0.49) TSHRCETPSRCCA1CA2
SCHEMBL8469027 0.77 TSHR (0.61) TSHRCETPSRCPDPK1MTOR
SCHEMBL3072265 0.77 TSHR (0.43) TSHRCETPSRCCA1CA2
SCHEMBL3067247 0.76 TSHR (0.42) TSHRSRCCA1CA2CA9
SCHEMBL7074455 0.75 HPGD (0.43) TSHRCA1CA2CA9CA12
SCHEMBL6830707 0.75 HPGD (0.43) TSHRCA1CA2CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3189125-B1 LUBRICATING COMPOSITIONS COMPRISING LIQUID ASHLESS ANTIOXIDANT ADDITIVE VANDERBILT CHEMICALS LLC (US) 2021-03-03 EP disclosed
CN-106604980-B Liquid ashless antioxidant additives for lubricating compositions 范德比尔特化学品有限责任公司 2020-04-17 CN disclosed
EP-3334811-A1 NOVEL ALKYLATED DIPHENYLAMINE DERIVATIVES OF TRIAZOLE AND LUBRICATING COMPOSITIONS CONTAINING THE SAME Vanderbilt Chemicals, LLC (US) 2018-06-20 EP disclosed
EP-3334808-A1 IMPROVED ANTIOXIDANT COMPOSITIONS AND LUBRICATING COMPOSITIONS CONTAINING THE SAME Vanderbilt Chemicals, LLC (US) 2018-06-20 EP disclosed
US-9994531-B2 Antioxidant compositions and lubricating compositions containing the same VANDERBILT CHEMICALS, LLC (US) 2018-06-12 US disclosed
US-9783759-B2 Liquid ashless antioxidant additive for lubricating compositions VANDERBILT CHEMICALS, LLC (US) 2017-10-10 US disclosed
EP-3189125-A1 LIQUID ASHLESS ANTIOXIDANT ADDITIVE FOR LUBRICATING COMPOSITIONS Vanderbilt Chemicals, LLC (US) 2017-07-12 EP disclosed
WO-2017030784-A1 IMPROVED ANTIOXIDANT COMPOSITIONS AND LUBRICATING COMPOSITIONS CONTAINING THE SAME VANDERBILT CHEMICALS, LLC (US) 2017-02-23 WO disclosed
WO-2017030783-A1 NOVEL ALKYLATED DIPHENYLAMINE DERIVATIVES OF TRIAZOLE AND LUBRICATING COMPOSITIONS CONTAINING THE SAME VANDERBILT CHEMICALS, LLC (US) 2017-02-23 WO disclosed
US-20170044113-A1 NOVEL ALKYLATED DIPHENYLAMINE DERIVATIVES OF TRIAZOLE AND LUBRICATING COMPOSITIONS CONTAINING THE SAME VANDERBILT CHEMICALS, LLC (US) 2017-02-16 US disclosed
US-6251840-B1 MIXTURE OF OIL, 2,5-DIMERCAPTO-1,3,4-THIADIAZOLE OR DERIVATIVES, ANTIFOAM AGENT, AND PHOSPHORIC ACID; AUTOMATIC TRANSMISSION FLUID WITH IMPROVED ANTIWEAR, ANTIFOAMING AND LOW TEMPERATURE VISCOSITY PROPERTIES THE LUBRIZOL CORPORATION 2001-06-26 US disclosed
US-6235686-B1 N-HETEROCYCLE POLYMERS AS OIL ADDITIVE R.T. VANDERBILT COMPANY, INC. 2001-05-22 US disclosed
EP-0761805-B1 Lubrication fluids for reduced air entrainment and improved gear protection LUBRIZOL CORP (US) 2001-03-14 EP disclosed
US-6133210-A COMPOSITION COMPRISING POLYMERIC CARBOXYLIC ESTER VISCOSITY IMPROVER AND HYDROCARBYL GROUP SUBSTITUTED ASHLESS DISPERSANT THE LUBRIZOL CORPORATION (US) 2000-10-17 US disclosed
EP-0969077-A2 Homogeneous additive concentrates for preparing lubricating oil compositions The Lubrizol Corporation (US) 2000-01-05 EP disclosed
US-5858929-A CALCIUM SALT OF AN OVERBASED SULFONIC ACID, PHOSPHORIC ACID, THREE FRICTION MODIFIERS, DISUBSTITUTED HYDROGEN PHOSPHITE ANTIWEAR AGENTS, POLYMETHACRYLATE DISPERSANT VISCOSITY MODIFIER OR MALEIC ANHYDRIDE/STYRENE CO-POLYMER, ALKOXYLATED THE LUBRIZOL CORPORATION (US) 1999-01-12 US disclosed
US-5759965-A OVERBASED COMPOUND; AUTOMATIC TRANSMISSION FLUID THE LUBRIZOL CORPORATION (US) 1998-06-02 US disclosed
EP-0769546-A2 Antiwear enhancing composition for lubricants and functional fluids The Lubrizol Corporation (US) 1997-04-23 EP disclosed
EP-0761805-A2 Lubrication fluids for reduced air entrainment and improved gear protection The Lubrizol Corporation (US) 1997-03-12 EP disclosed
EP-0747464-A1 A composition for providing anti-shudder friction durability performance for automatic transmissions The Lubrizol Corporation (US) 1996-12-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170044113-A1 NOVEL ALKYLATED DIPHENYLAMINE DERIVATIVES OF TRIAZOLE AND LUBRICATING COMPOSITIONS CONTAINING THE SAME HTR3A, HTR3D, AADAC TSHR 3068/4885CETP 1333/4885SRC 2156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.