Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 13/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.63 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.63 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.63 |
| ▸ | MITF | O75030 | 1/20 | 0.63 |
| ▸ | MTOR | P42345 | 1/20 | 0.63 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | CTSB | P07858 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3627022 | 0.90 | MAPT (0.79) | ALDH1A1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL6264295 | 0.90 | MAPT (0.79) | ALDH1A1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL6320708 | 0.85 | MAPT (0.81) | ALDH1A1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL5440898 | 0.85 | CTSB (0.67) | ALDH1A1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL29741465 | 0.85 | MAPT (0.81) | ALDH1A1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL24715880 | 0.81 | MAPT (0.55) | ALDH1A1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL28520810 | 0.81 | MTOR (0.64) | ALDH1A1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL22858551 | 0.81 | CTSB (0.75) | ALDH1A1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL29577374 | 0.81 | CTSB (0.75) | ALDH1A1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL24701133 | 0.80 | MTOR (0.83) | ALDH1A1KMT2AMAPTSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070254894-A1 | Novel small molecules with selective cytotoxicity against human microvascular endothelial cell proliferation | KANE JOHN L JR | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254894-A1 | Novel small molecules with selective cytotoxicity against human microvascular endothelial cell proliferation | MKI67, VEGFA, KDR | ALDH1A1 1480/4885KMT2A 4653/4885MAPT 4441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.