Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.73 |
| ▸ | MAPT | P10636 | 4/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | ALPL | P05186 | 1/20 | 0.62 |
| ▸ | ALPI | P09923 | 1/20 | 0.62 |
| ▸ | ALPG | P10696 | 1/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11007347 | 0.89 | ALDH1A1 (0.72) | GAAALDH1A1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL28401841 | 0.88 | ALDH1A1 (0.82) | GAAALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL30362713 | 0.88 | ALDH1A1 (0.82) | GAAALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL30362755 | 0.87 | GAA (0.77) | GAAALDH1A1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL28401851 | 0.87 | GAA (0.77) | GAAALDH1A1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL28398542 | 0.85 | GAA (0.76) | GAAALDH1A1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL30362785 | 0.85 | GAA (0.76) | GAAALDH1A1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL6442535 | 0.85 | GAA (0.67) | GAAALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL6814971 | 0.85 | KMT2A (0.65) | GAAALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL6812340 | 0.84 | KMT2A (0.61) | GAAALDH1A1MAPTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111138358-B | USP8 inhibitor and preparation method and application thereof | 中国药科大学 | 2023-04-18 | — | — | CN | disclosed |
| CN-111138358-A | USP8 inhibitor and preparation method and application thereof | 中国药科大学 | 2020-05-12 | — | — | CN | disclosed |
| CN-101129295-B | There is the binary initiator system of good storage stability and especially suitable for acidic system | HERAEUS KULZER GMBH (DE) | 2016-02-10 | — | — | CN | disclosed |
| CN-101129295-A | 2-component initiator system (amine free) with storage stability and especially suitable for acidic systems | HERAEUS KULZER GMBH (DE) | 2008-02-27 | — | — | CN | disclosed |
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |