Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.63 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.63 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.61 |
| ▸ | PPARG | P37231 | 7/20 | 0.61 |
| ▸ | PPARD | Q03181 | 7/20 | 0.61 |
| ▸ | PPARA | Q07869 | 7/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.61 |
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | TLR2 | O60603 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | FABP4 | P15090 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.61 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | PDE4A | P27815 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879001 | 1.00 | FFAR4 (0.63) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL26614829 | 0.98 | FFAR4 (0.60) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL2113762 | 0.96 | FFAR4 (0.69) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL5879088 | 0.96 | FFAR4 (0.69) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL27917758 | 0.96 | FFAR4 (0.69) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL5879015 | 0.96 | FFAR4 (0.69) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL626863 | 0.96 | FFAR4 (0.69) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL5878798 | 0.96 | FFAR4 (0.69) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL28767027 | 0.96 | FFAR4 (0.69) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL27917702 | 0.96 | FFAR4 (0.69) | FFAR4FFAR1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018122626-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CHRONIC PAIN | CELLIX BIO PRIVATE LIMITED (IN) | 2018-07-05 | — | — | WO | disclosed |
| WO-2018096405-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF ORAL INFECTIOUS DISEASES | CELLIX BIO PRIVATE LIMITED (IN) | 2018-05-31 | — | — | WO | disclosed |
| US-20160031935-A1 | SMALL MOLECULE MODULATORS OF PCSK9 AND METHODS OF USE THEREOF | NUCHEM THERAPEUTICS (CA) | 2016-02-04 | — | — | US | disclosed |
| EP-2961765-A1 | SMALL MOLECULE MODULATORS OF PCSK9 AND METHODS OF USE THEREOF | Adaerata, Limited Partnership (CA) | 2016-01-06 | — | — | EP | disclosed |
| WO-2014139008-A1 | SMALL MOLECULE MODULATORS OF PCSK9 AND METHODS OF USE THEREOF | ADAERATA, LIMITED PARTNERSHIP (CA) | 2014-09-18 | — | — | WO | disclosed |
| US-20070036841-A1 | Method of enhancing an ornithine-urea cycle in ruminant gut tissues to detoxify ammonia and increase local urea recycling to the rumen for microbial protein synthesis | BEQUETTE BRIAN JAMES | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160031935-A1 | SMALL MOLECULE MODULATORS OF PCSK9 AND METHODS OF USE THEREOF | PCSK9, PCSK7, PCSK6 | FFAR4 1289/4885FFAR1 854/4885GPR84 2314/4885 |
| US-20070036841-A1 | Method of enhancing an ornithine-urea cycle in ruminant gut tissues to detoxify ammonia and increase local urea recycling to the rumen for microbial protein synthesis | OAT, OTC, ODC1 | FFAR4 2541/4885FFAR1 2278/4885GPR84 1848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.