SCHEMBL5451205

SCHEMBL5451205

CC(C)CC(=O)C(C)(Cl)Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.46
ALDH1A1 P00352 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CA2 P00918 2/20 0.40
GAA P10253 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP3 P08254 1/20 0.31
MMP9 P14780 1/20 0.31
MMP13 P45452 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA9 Q16790 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
GPR55 Q9Y2T6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5322329 0.81 CYP2C19 (0.48) CYP2C19ALDH1A1TDP1CA2GAA
SCHEMBL269050 0.78 ALDH1A1 (0.48) CYP2C19ALDH1A1TDP1CA2SMN1; SMN2
Methyl Isobutyl Ketone SCHEMBL28228269 0.74 ALDH1A1 (0.74) CYP2C19ALDH1A1TDP1CA2GAA
SCHEMBL13554068 0.74 ALDH1A1 (0.43) CYP2C19ALDH1A1TDP1CA2SMN1; SMN2
SCHEMBL20931107 0.72 ALDH1A1 (0.42) CYP2C19ALDH1A1TDP1CA2SMN1; SMN2
SCHEMBL3648823 0.72 ALDH1A1 (0.42) CYP2C19ALDH1A1TDP1CA2SMN1; SMN2
SCHEMBL10943994 0.72 ALDH1A1 (0.48) CYP2C19ALDH1A1TDP1CA2GAA
SCHEMBL28957295 0.71
Chloromethane SCHEMBL27866026 0.71 CYP2C19 (0.68) CYP2C19ALDH1A1TDP1CA2GAA
SCHEMBL1492542 0.70 ALDH1A1 (0.46) CYP2C19ALDH1A1TDP1CA2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070249660-A1 Pharmacologically Acceptable Salts of Clopidogrel SIEGFRIED GENERICS INTERNATIONAL AG (CH) 2007-10-25 US disclosed