SCHEMBL5451231

SCHEMBL5451231

CCC(=O)OC=C([SiH3])OC(=O)CC

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
NAAA Q02083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8526100 0.73
SCHEMBL3032644 0.73 ALDH1A1 (0.36) ALDH1A1NAAA
SCHEMBL28223804 0.71
SCHEMBL4839246 0.69 ALDH1A1 (0.41) ALDH1A1NAAA
SCHEMBL9276 0.68
SCHEMBL126507 0.67
SCHEMBL525131 0.67
SCHEMBL10781709 0.67 ALDH1A1 (0.41) ALDH1A1
SCHEMBL10781714 0.67 ALDH1A1 (0.41) ALDH1A1
SCHEMBL11129045 0.67 ALDH1A1 (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070173935-A1 Nucleus pulposus augmentation pretreatment technique DEPUY SPINE, INC. 2007-07-26 US claimed
US-20070173935-A1 Nucleus pulposus augmentation pretreatment technique DEPUY SPINE, INC. 2007-07-26 US disclosed
EP-0680977-B1 Copolymers containing hydroxyl and carboxyl groups, their preparation and their use in high solid coatings HOECHST AG (DE) 1998-04-01 EP disclosed
EP-0680977-A1 Copolymers containing hydroxyl and carboxyl groups, their preparation and their use in high solid coatings HOECHST AKTIENGESELLSCHAFT (DE) 1995-11-08 EP disclosed