Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.47 |
| ▸ | HTR2A | P28223 | 4/20 | 0.47 |
| ▸ | HTR2B | P41595 | 4/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12504901 | 0.81 | HTR2C (0.49) | HTR2CHTR2AHTR2BTAAR1TSHR | |
| SCHEMBL12504944 | 0.81 | HTR2A (0.49) | HTR2CHTR2AHTR2BTAAR1TSHR | |
| SCHEMBL16464059 | 0.81 | HTR2C (0.49) | HTR2CHTR2AHTR2BTAAR1TSHR | |
| SCHEMBL12504962 | 0.80 | HTR2C (0.48) | HTR2CHTR2AHTR2BTAAR1TSHR | |
| SCHEMBL2369359 | 0.76 | HTR2C (0.50) | HTR2CHTR2AHTR2BTAAR1TSHR | |
| Oxalic Acid SCHEMBL9797203 | 0.74 | HTR2A (0.43) | HTR2CHTR2AHTR2BTAAR1TSHR | |
| Hydrochloric Acid SCHEMBL3694587 | 0.72 | HTR2C (0.60) | HTR2CHTR2AHTR2BTAAR1DRD2 | |
| SCHEMBL9155067 | 0.72 | HTR2A (0.49) | HTR2CHTR2AHTR2BTAAR1OPRM1 | |
| SCHEMBL175082 | 0.72 | CYP1A2 (0.41) | HTR2CHTR2AHTR2BTAAR1TSHR | |
| SCHEMBL1520386 | 0.71 | HTR2C (0.62) | HTR2CHTR2AHTR2BTAAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185089-A1 | Benzazepine derivatives for the treatment of neurological and psychiatric disorders | GLAXO GROUP LIMITED (GB) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185089-A1 | Benzazepine derivatives for the treatment of neurological and psychiatric disorders | CNR2, GRIN2C, GRIN2B | HTR2C 12/4885HTR2A 78/4885HTR2B 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.