Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.37 |
| ▸ | DRD1 | P21728 | 9/20 | 0.37 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | DRD5 | P21918 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.35 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Orotic Acid SCHEMBL174876 | 0.77 | HTR2C (0.59) | TAAR1HTR2AHTR2CHTR2BLMNA | |
| Orotic Acid SCHEMBL162920 | 0.75 | ALDH1A1 (0.45) | TAAR1HTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL16464059 | 0.74 | HTR2C (0.49) | TAAR1HTR2AHTR2CHTR2BDRD1 | |
| SCHEMBL12504944 | 0.74 | HTR2A (0.49) | TAAR1HTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL12504901 | 0.74 | HTR2C (0.49) | TAAR1HTR2AHTR2CHTR2BDRD1 | |
| SCHEMBL12504962 | 0.73 | HTR2C (0.48) | TAAR1HTR2AHTR2CHTR2BDRD1 | |
| Orotic Acid SCHEMBL175081 | 0.72 | ALDH1A1 (0.62) | CYP1A2HTR2CHTR2BMEN1KMT2A | |
| SCHEMBL5451237 | 0.72 | HTR2C (0.47) | TAAR1HTR2AHTR2CHTR2BDRD1 | |
| Lorcaserin SCHEMBL175008 | 0.67 | HTR2A (0.63) | HTR2AHTR2CHTR2BLMNAALDH1A1 | |
| Lorcaserin SCHEMBL170984 | 0.67 | HTR2A (0.63) | HTR2AHTR2CHTR2BLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012030953-A1 | 5-HT2C RECEPTOR AGONISTS IN THE TREATMENT OF DISORDERS AMELIORATED BY REDUCTION OF NOREPINEPHRINE LEVEL | ARENA PHARMACEUTICALS, INC. (US) | 2012-03-08 | — | — | WO | disclosed |