⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9545155 | 0.84 | MIF (0.33) | — | |
| SCHEMBL9545151 | 0.84 | MIF (0.33) | — | |
| SCHEMBL5444527 | 0.75 | — | — | |
| SCHEMBL13309326 | 0.71 | TSHR (0.34) | — | |
| SCHEMBL445941 | 0.70 | — | — | |
| SCHEMBL524350 | 0.70 | — | — | |
| SCHEMBL93534 | 0.69 | — | — | |
| SCHEMBL828525 | 0.69 | — | — | |
| SCHEMBL2719646 | 0.69 | MIF (0.31) | — | |
| SCHEMBL14763975 | 0.69 | TRPA1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070173935-A1 | Nucleus pulposus augmentation pretreatment technique | DEPUY SPINE, INC. | 2007-07-26 | — | — | US | claimed |
| US-20070173935-A1 | Nucleus pulposus augmentation pretreatment technique | DEPUY SPINE, INC. | 2007-07-26 | — | — | US | disclosed |
| EP-0680977-B1 | Copolymers containing hydroxyl and carboxyl groups, their preparation and their use in high solid coatings | HOECHST AG (DE) | 1998-04-01 | — | — | EP | disclosed |
| EP-0680977-A1 | Copolymers containing hydroxyl and carboxyl groups, their preparation and their use in high solid coatings | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-11-08 | — | — | EP | disclosed |