Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 10/20 | 0.68 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.68 |
| ▸ | PDE4A | P27815 | 8/20 | 0.68 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.68 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.68 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.68 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | PDE1A | P54750 | 1/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27256851 | 0.88 | ADORA2B (0.68) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL1892011 | 0.83 | ADORA2B (0.92) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL7326960 | 0.83 | ADORA2A (0.67) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL59949 | 0.83 | ADORA2B (0.72) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL9432924 | 0.82 | ADORA2B (0.71) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL11661797 | 0.82 | ADORA2B (0.89) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL21381249 | 0.82 | ADORA2B (0.89) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL6233166 | 0.81 | ADORA2B (1.00) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL31081359 | 0.81 | ADORA2B (0.74) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL27395394 | 0.81 | ADORA2B (1.00) | ADORA2BADORA2APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253176-B1 | Immunosuppressive effects of 8-substituted xanthine derivatives | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2007-08-07 | — | — | US | disclosed |
| EP-0956855-B1 | Immunosuppressive effects of 8 substituted xanthine derivatives | LEUVEN K U RES & DEV (BE) | 2003-03-12 | — | — | EP | disclosed |
| EP-0956855-A1 | Immunosuppressive effects of 8-substituted xanthine derivatives | K.U. Leuven Research & Development (BE) | 1999-11-17 | — | — | EP | disclosed |
| WO-1998030900-A2 | SCREENING METHOD FOR COMPOUNDS ACTIVE IN TREATING MYOPIA AND HYPERMETROPIA | KLAUS TRIER APS (DK) | 1998-07-16 | — | — | WO | disclosed |
| US-4983514-A | Adding the enzyme inhibitors and a prostaglandin to a blood sample removed from the subject body and measuring the platelet coagulation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-08 | — | — | US | disclosed |