Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.68 |
| ▸ | TSHR | P16473 | 9/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 8/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | HTT | P42858 | 4/20 | 0.68 |
| ▸ | CASP1 | P29466 | 3/20 | 0.68 |
| ▸ | USP2 | O75604 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | GUSB | P08236 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5464839 | 0.84 | ALDH1A1 (0.65) | ALDH1A1KDM4EHSD17B10TSHRNPSR1 | |
| SCHEMBL4069208 | 0.83 | KDM4E (0.60) | ALDH1A1KDM4EHSD17B10TSHRNPSR1 | |
| SCHEMBL5455222 | 0.83 | ALDH1A1 (0.62) | ALDH1A1KDM4EHSD17B10TSHRNPSR1 | |
| SCHEMBL4077969 | 0.82 | KDM4E (0.61) | ALDH1A1KDM4EHSD17B10TSHRNPSR1 | |
| SCHEMBL5463453 | 0.80 | KDM4E (0.59) | ALDH1A1KDM4EHSD17B10TSHRNPSR1 | |
| SCHEMBL5459170 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KDM4EHSD17B10TSHRNPSR1 | |
| SCHEMBL4079782 | 0.78 | KDM4E (0.56) | ALDH1A1KDM4EHSD17B10TSHRNPSR1 | |
| SCHEMBL4073672 | 0.78 | ALDH1A1 (0.58) | ALDH1A1KDM4EHSD17B10TSHRNPSR1 | |
| SCHEMBL5448947 | 0.78 | KDM4E (0.66) | ALDH1A1KDM4EHSD17B10TSHRNPSR1 | |
| SCHEMBL4070699 | 0.77 | ALDH1A1 (0.55) | ALDH1A1KDM4EHSD17B10TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070287706-A1 | Certain substituted quinolones, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2007-12-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287706-A1 | Certain substituted quinolones, compositions, and uses thereof | ABCG2, ATP5ME, ATP5MG | ALDH1A1 1055/4885KDM4E 2403/4885HSD17B10 1580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.