SCHEMBL5451661

SCHEMBL5451661

CCCCCC(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL61375 1.00
SCHEMBL23034519 0.97 CES2 (0.50)
SCHEMBL465782 0.97 CES2 (0.50)
SCHEMBL4854234 0.97 CES2 (0.50)
SCHEMBL24234728 0.97 CES2 (0.50)
SCHEMBL83980 0.97 CES2 (0.50)
SCHEMBL6934289 0.97 CES2 (0.50)
SCHEMBL11245966 0.97 CES2 (0.50)
SCHEMBL22268768 0.97 CES2 (0.50)
SCHEMBL1697656 0.97 CES2 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240116963-A1 DENDRIMERS HAVING THIOPHOSPHORAMIDATE PATTERNS AND DERIVATIVES INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2024-04-11 US disclosed
US-20230235190-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS Crime Science Technology (FR) 2023-07-27 US disclosed
EP-4164891-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS Crime Science Technology (FR) 2023-04-19 EP disclosed
US-20230013304-A1 N2-ARYLMETHYL-4-HALOALKYL-PYRIDAZIN-3-ONE CFTR MODULATORS FOR THE TREATMENT OF CYSTIC FIBROSIS ECOLE NORMALE SUPERIEURE DE LYON (FR) 2023-01-19 US disclosed
EP-4081530-A1 DENDRIMERS HAVING THIOPHOSPHORAMIDATE PATTERNS AND DERIVATIVES Centre National de la Recherche Scientifique (CNRS) (FR) 2022-11-02 EP disclosed
CN-114945368-A N2-arylmethyl-4-haloalkyl-pyridazin-3-one compounds and uses thereof 香槟-阿尔登兰斯大学 2022-08-26 CN disclosed
CN-114867731-A Dendritic macromolecule with sulfur and phosphoric amide crystal structure and derivative thereof 国家科学研究中心 2022-08-05 CN disclosed
WO-2021130454-A1 DENDRIMERS HAVING THIOPHOSPHORAMIDATE PATTERNS AND DERIVATIVES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS - (FR) 2021-07-01 WO disclosed
WO-2021105641-A1 N2-ARYLMETHYL-4-HALOALKYL-PYRIDAZIN-3-ONE CFTR MODULATORS FOR THE TREATMENT OF CYSTIC FIBROSIS UNIVERSITE DE REIMS CHAMPAGNE-ARDENNE (FR) 2021-06-03 WO disclosed
US-20170137419-A1 DERIVATIVES OF 2H-PYRAZOLO[4,3-C]QUINOLIN-3(5H)-ONE AND USE THEREOF INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2017-05-18 US disclosed
EP-0188895-B1 HYDROPHILIC SILICONE-ORGANIC COPOLYMER ELASTOMERS DOW CORNING CORPORATION (US) 1990-08-22 EP disclosed
EP-0191237-B1 AQUEOUS EMULSIONS CONTAINING HYDROPHILIC SILICONE-ORGANIC COPOLYMERS DOW CORNING CORPORATION (US) 1990-05-16 EP disclosed
EP-0190505-B1 HYDROPHILIC SILICONE-ORGANIC COPOLYMER ELASTOMERS DOW CORNING CORPORATION (US) 1990-05-09 EP disclosed
US-4851216-A BLOCK COPOLYMER CONTAINING POLYETHER AND AN UNSATURATED MONOMER; TRANSDERMAL MEMBRANES DOW CORNING CORPORATION (US) 1989-07-25 US disclosed
US-4833218-A Hydrophilic silicone-organic copolymer elastomers containing bioactine agent DOW CORNING CORPORATION (US) 1989-05-23 US disclosed
EP-0191237-A1 Aqueous emulsions containing hydrophilic silicone-organic copolymers DOW CORNING CORPORATION (US) 1986-08-20 EP disclosed
EP-0190505-A1 Hydrophilic silicone-organic copolymer elastomers DOW CORNING CORPORATION (US) 1986-08-13 EP disclosed
EP-0188895-A1 Hydrophilic silicone-organic copolymer elastomers DOW CORNING CORPORATION (US) 1986-07-30 EP disclosed
US-4600751-A Hydrophilic silicone-organic copolymer elastomers DOW CORNING CORPORATION (US) 1986-07-15 US disclosed
US-4584337-A Aqueous emulsions containing hydrophilic silicone-organic copolymers DOW CORNING CORPORATION (US) 1986-04-22 US disclosed