Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14624305 | 1.00 | F10 (0.51) | F10KCNH2 | |
| SCHEMBL14624306 | 0.89 | F10 (0.39) | F10KCNH2 | |
| SCHEMBL14622800 | 0.85 | F10 (0.45) | F10 | |
| SCHEMBL4598083 | 0.81 | F10 (0.47) | F10KCNH2 | |
| SCHEMBL14623848 | 0.80 | F10 (0.50) | F10 | |
| SCHEMBL4598652 | 0.77 | F10 (0.49) | F10KCNH2 | |
| SCHEMBL4597978 | 0.76 | F10 (0.60) | F10 | |
| SCHEMBL4597237 | 0.76 | F10 (0.60) | F10 | |
| SCHEMBL5464203 | 0.74 | F10 (0.48) | F10KCNH2 | |
| SCHEMBL14097938 | 0.74 | F10 (0.66) | F10KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007009883-A1 | NOVEL HETEROARYL FUSED CYCLIC AMINES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-01-25 | — | — | WO | disclosed |
| US-20070015812-A1 | Factor Xa inhibitors | F. HOFFMANN-LA ROCHE AG, A SWISS COMPANY (CH) | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015812-A1 | Factor Xa inhibitors | F12, F11, F2 | F10 4/4885KCNH2 1541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.