Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.68 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | STAT3 | P40763 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NT5E | P21589 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | TYK2 | P29597 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5473994 | 0.92 | ROCK2 (0.65) | ROCK2ROCK1KDM4EL3MBTL1LMNA | |
| SCHEMBL3687151 | 0.89 | ROCK2 (0.72) | ROCK2ROCK1KDM4EL3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL5466118 | 0.88 | ROCK2 (0.72) | ROCK2ROCK1KDM4EL3MBTL1LMNA | |
| SCHEMBL2790408 | 0.85 | ROCK2 (0.69) | ROCK2ROCK1KDM4EL3MBTL1LMNA | |
| SCHEMBL2793935 | 0.85 | ROCK2 (0.69) | ROCK2ROCK1KDM4EL3MBTL1LMNA | |
| SCHEMBL2795043 | 0.85 | ROCK2 (0.69) | ROCK2ROCK1KDM4EL3MBTL1LMNA | |
| SCHEMBL2792305 | 0.84 | ROCK2 (0.68) | ROCK2ROCK1KDM4EL3MBTL1LMNA | |
| SCHEMBL6557935 | 0.83 | ROCK2 (0.68) | ROCK2ROCK1KDM4EL3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL2794136 | 0.83 | ROCK2 (0.70) | ROCK2ROCK1KDM4EL3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL2789873 | 0.83 | ROCK2 (0.70) | ROCK2ROCK1KDM4EL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191420-A1 | Kinase inhibitors | DEVGEN NV | 2007-08-16 | — | — | US | claimed |
| EP-1715862-A1 | KINASE INHIBITORS | Devgen NV (BE) | 2006-11-02 | — | — | EP | claimed |
| WO-2005082367-A1 | KINASE INHIBITORS | DEVGEN NV (BE) | 2005-09-09 | — | — | WO | claimed |
| US-20070191420-A1 | Kinase inhibitors | DEVGEN NV | 2007-08-16 | — | — | US | disclosed |
| US-20070191420-A1 | Kinase inhibitors | DEVGEN NV | 2007-08-16 | — | — | US | disclosed |
| US-20070191420-A1 | Kinase inhibitors | DEVGEN NV | 2007-08-16 | — | — | US | disclosed |
| US-RE39592-E1 | Extended release growth promoting two component composition | INTERVET INC. (NL) | 2007-04-24 | — | — | US | disclosed |
| US-6498153-B1 | SUCH AS 17-BETA-ACETOXYESTRA-4,9,11-TRIEN-3-ONE, 17-BETA-PROPIONYLOXY-4-ANDROSTEN-3-ONE, AND/OR 3,4,5,6,9,10,11,12-DECAHYDRO-7,14,16-TRI-HYDROXY-3-METHYL-1H-2-BENZOXACYCLO -TETRADECIN-1-ONE AND A BIODEGRADABLE POLYMER | AKZO NOBEL N.V. (NL) | 2002-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191420-A1 | Kinase inhibitors | ROCK1, ROCK2, MAP3K20 | ROCK2 2/4885ROCK1 1/4885KDM4E 569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.