SCHEMBL5451954

SCHEMBL5451954

CN(C)CCC(NC(=O)CCc1ccc(C(F)(F)F)cc1)c1ccc(Cl)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 19/20 1.00
CNR2 P34972 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5431996 0.99 UTS2R (0.98) UTS2R
SCHEMBL5467811 0.90 UTS2R (1.00) UTS2R
Hydrochloric Acid SCHEMBL5458778 0.89 UTS2R (0.98) UTS2R
Hydrochloric Acid SCHEMBL5464581 0.88 UTS2R (0.98) UTS2RCNR2
Hydrochloric Acid SCHEMBL5458755 0.84 UTS2R (0.98) UTS2R
SCHEMBL6092298 0.84 UTS2R (1.00) UTS2R
Hydrochloric Acid SCHEMBL5464571 0.83 UTS2R (0.98) UTS2R
Oxalic Acid SCHEMBL5452698 0.81 UTS2R (0.93) UTS2R
Hydrochloric Acid SCHEMBL5458298 0.78 UTS2R (0.98) UTS2RCNR2
SCHEMBL6102889 0.78 UTS2R (1.00) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070043104-A1 UII-modulating compounds and their use ACADIA PHARMACEUTICALS INC. 2007-02-22 US claimed
WO-2006135694-A2 UII-MODULATING COMPOUNDS AND THEIR USE ACADIA PHARMACEUTICALS INC. (US) 2006-12-21 WO claimed
US-20070043104-A1 UII-modulating compounds and their use ACADIA PHARMACEUTICALS INC. 2007-02-22 US disclosed
WO-2006135694-A2 UII-MODULATING COMPOUNDS AND THEIR USE ACADIA PHARMACEUTICALS INC. (US) 2006-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070043104-A1 UII-modulating compounds and their use UTS2R, GPR17, GPR119 UTS2R 1/4885CNR2 409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.