Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14428685 | 0.79 | ALDH1A1 (0.55) | ALDH1A1CYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL3873785 | 0.67 | CYP2C9 (0.63) | ALDH1A1CYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL20768992 | 0.65 | SMYD3 (0.84) | SMYD3 | |
| SCHEMBL18705888 | 0.64 | SMYD3 (0.78) | KMT2ASMYD3 | |
| SCHEMBL18706475 | 0.63 | SMYD3 (0.70) | HSD17B10CASP1SMYD3 | |
| SCHEMBL15445064 | 0.63 | NPSR1 (0.67) | ALDH1A1CYP2C19KDM4ENPSR1KMT2A | |
| SCHEMBL18705707 | 0.62 | SMYD3 (0.75) | SMYD3 | |
| SCHEMBL18706036 | 0.62 | SMYD3 (1.00) | ALDH1A1MAPK1KMT2AMEN1MAPT | |
| SCHEMBL18706397 | 0.62 | SMYD3 (1.00) | ALDH1A1MAPK1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL18705953 | 0.61 | SMYD3 (0.73) | SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191400-A1 | Pharmaceutical compositions comprising anti-inflammatory quinazolinecarboxamide derivatives | RIMONYX PHARMACEUTICALS LTD. (IL) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191400-A1 | Pharmaceutical compositions comprising anti-inflammatory quinazolinecarboxamide derivatives | HPSE, SSB, HCLS1 | ALDH1A1 2758/4885CYP3A4 1778/4885CYP2C9 1557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.