Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 7/20 | 0.40 |
| ▸ | HTR2B | P41595 | 5/20 | 0.40 |
| ▸ | HTR2A | P28223 | 4/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | HRH2 | P25021 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24933586 | 0.82 | KDM4E (0.44) | ALDH1A1HPGDMAPK1GAA | |
| SCHEMBL14392489 | 0.81 | HPGD (0.59) | ALDH1A1HPGDMEN1HTTKMT2A | |
| SCHEMBL2322279 | 0.81 | HPGD (0.59) | ALDH1A1HPGDMEN1HTTKMT2A | |
| SCHEMBL7813169 | 0.80 | HPGD (0.58) | ALDH1A1HPGDMEN1HTTKMT2A | |
| SCHEMBL1880355 | 0.79 | HTR2C (0.42) | ALDH1A1HPGDMEN1HTTKMT2A | |
| SCHEMBL9699860 | 0.79 | HPGD (0.43) | ALDH1A1HPGDMEN1HTTKMT2A | |
| SCHEMBL9710314 | 0.79 | HPGD (0.43) | ALDH1A1HPGDMEN1HTTKMT2A | |
| SCHEMBL7143238 | 0.79 | HPGD (0.69) | ALDH1A1HPGDMEN1HTTKMT2A | |
| SCHEMBL31676672 | 0.79 | HPGD (0.56) | ALDH1A1HPGDMEN1HTTKMT2A | |
| SCHEMBL5645943 | 0.79 | HPGD (0.56) | ALDH1A1HPGDMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297379-B2 | Polyfluorinated fused aromatics and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2007-11-20 | — | — | US | disclosed |
| CN-1827572-A | Cyclohexyl biphenyls liquid crystal compounds | XIAN MODERN CHEMISTRY RES INST (CN) | 2006-09-06 | — | — | CN | disclosed |
| US-20050255258-A1 | Polyfluorinated fused aromatics and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050255258-A1 | Polyfluorinated fused aromatics and their use in liquid-crystal mixtures | SCO2, CHRM1, CBR1 | ALDH1A1 1301/4885HPGD 3247/4885MEN1 687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.