Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5452264 | 0.82 | ALDH1A1 (0.56) | GAAALDH1A1HPGDMAPK1 | |
| SCHEMBL20578753 | 0.81 | POLB (0.50) | POLBPKMCTSLCTSSCTSK | |
| SCHEMBL2094490 | 0.79 | KDM4E (0.44) | KDM4EPOLBPKMAAK1L3MBTL1 | |
| SCHEMBL15758450 | 0.79 | SMN1; SMN2 (0.50) | KDM4EPOLBPKML3MBTL1SMN1; SMN2 | |
| SCHEMBL14290417 | 0.79 | PTGDR2 (0.64) | POLBPTGDR2L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL5000471 | 0.79 | KDM4E (0.48) | KDM4EPOLBPKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL15677337 | 0.77 | KDM4E (0.42) | KDM4EPOLBPKMAAK1L3MBTL1 | |
| SCHEMBL14290421 | 0.76 | PTGDR2 (0.62) | PTGDR2MAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL31083916 | 0.76 | PTGDR2 (0.53) | KDM4EPOLBPTGDR2L3MBTL1GAA | |
| SCHEMBL1509935 | 0.76 | HPGD (0.51) | AAK1L3MBTL1GAASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009475-A1 | ROCK2 INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-02-02 | — | — | WO | disclosed |