Prolintane

Prolintane

SCHEMBL54523

CCCC(Cc1ccccc1)N1CCCC1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 5/20 0.54
SLC6A3 Q01959 5/20 0.54
SLC6A4 P31645 4/20 0.54
CYP3A4 P08684 5/20 0.51
CYP2C19 P33261 5/20 0.51
CYP1A2 P05177 4/20 0.51
CYP2D6 P10635 4/20 0.51
TSHR P16473 2/20 0.51
IDO1 P14902 1/20 0.51
MC4R P32245 4/20 0.50
OPRM1 P35372 2/20 0.43
OPRK1 P41145 2/20 0.43
OPRD1 P41143 1/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
RAB9A P51151 1/20 0.40
HRH3 Q9Y5N1 1/20 0.40
CYP2C9 P11712 3/20 0.40
KCNH2 Q12809 3/20 0.40
LMNA P02545 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Prolintane SCHEMBL122811 0.98 SLC6A2 (0.53) SLC6A2SLC6A3SLC6A4CYP3A4CYP2C19
Prolintane SCHEMBL1652326 0.97 SLC6A2 (0.51) SLC6A2SLC6A3SLC6A4CYP3A4CYP2C19
SCHEMBL4896743 0.89 CYP1A2 (0.51) SLC6A2SLC6A3SLC6A4CYP3A4CYP2C19
SCHEMBL5180934 0.89 SLC6A2 (0.50) SLC6A2SLC6A3SLC6A4CYP3A4CYP2C19
SCHEMBL20854155 0.87 CYP1A2 (0.50) SLC6A2SLC6A3SLC6A4CYP3A4CYP2C19
SCHEMBL12847327 0.86 CYP3A4 (0.54) SLC6A2SLC6A3SLC6A4CYP3A4CYP2C19
Hydrochloric Acid SCHEMBL11555126 0.85 CYP1A2 (0.48) SLC6A2SLC6A3SLC6A4CYP3A4CYP2C19
SCHEMBL12847334 0.84 CYP1A2 (0.57) SLC6A2SLC6A3SLC6A4CYP3A4CYP2C19
SCHEMBL5181150 0.83 HRH3 (0.44) SLC6A2SLC6A3SLC6A4MEN1KMT2A
SCHEMBL7837846 0.79 CYP3A4 (0.40) SLC6A2SLC6A3SLC6A4CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1830 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4722714-A1 SIMULTANEOUS ANALYSIS OF FOOD-BORNE DOPING SUBSTANCES USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (VFD: VACCINE FOR FOODBORNE DOPING) Korea Institute of Science and Technology (KR) 2026-04-08 EP claimed
US-12509598-B2 Process solution composition for polymer treatment comprising a fluorine compound, a ketone solvent, and a polar aprotic solvent DONGWOO FINE-CHEM CO., LTD. (KR) 2025-12-30 US claimed
EP-4633638-A1 TREATMENT OF PSYCHOLOGICAL FACTORS AFFECTING OTHER MEDICAL CONDITIONS (PFAOMC) Luminous Mind Inc. (US) 2025-10-22 EP claimed
EP-4615506-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES Sahin, Fikret (TR) 2025-09-17 EP claimed
WO-2024258363-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES SAHIN FIKRET (TR) 2024-12-19 WO claimed
WO-2024130044-A1 TREATMENT OF PSYCHOLOGICAL FACTORS AFFECTING OTHER MEDICAL CONDITIONS (PFAOMC) LUMINOUS MIND INC. (US) 2024-06-20 WO claimed
US-20230213415-A1 Method and System for Imaging and Analysis of a Biological Specimen THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2023-07-06 US claimed
US-11624685-B2 Method and system for imaging and analysis of a biological specimen The Board of Trustees of the Leland Sanford Junior Univeristy (US) 2023-04-11 US claimed
US-20220323380-A1 DRUG COMBINATION FOR USE IN THE TREATMENT OF INFLAMMATORY DISEASES ISANAS AG (CH) 2022-10-13 US claimed
EP-3986391-A1 DRUG COMBINATION FOR USE IN THE TREATMENT OF INFLAMMATORY DISEASES Isanas AG (CH) 2022-04-27 EP claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
US-6217904-B1 MIXTURES; ADMINISTERING IN CYCLES PHARMAQUEST LTD. (BM) 2001-04-17 US claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000059481-A1 PHARMACEUTICAL DOSAGE FORM FOR PULSATILE DELIVERY OF d-threo-METHYLPHENIDATE AND A SECOND CNS STIMULANT PHARMAQUEST LTD. (BM) 2000-10-12 WO claimed
WO-2000059479-A1 PHARMACEUTICAL DOSAGE FORM FOR PULSATILE DELIVERY OF METHYLPHENIDATE PHARMAQUEST LTD. (BM) 2000-10-12 WO claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
WO-1997041878-A1 TREATMENT OF MOOD DISORDERS WITH A GROWTH HORMONE SECRETAGOGUE MERCK & CO., INC. (US) 1997-11-13 WO claimed
EP-0174342-B1 BRAIN-SPECIFIC ANALOGUES OF CENTRALLY ACTING AMINES UNIVERSITY OF FLORIDA (US) 1989-12-20 EP claimed
EP-0174342-A1 BRAIN-SPECIFIC ANALOGUES OF CENTRALLY ACTING AMINES. UNIV FLORIDA (US) 1986-03-19 EP claimed
WO-1985003937-A1 BRAIN-SPECIFIC ANALOGUES OF CENTRALLY ACTING AMINES UNIVERSITY OF FLORIDA (US) 1985-09-12 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509598-B2 Process solution composition for polymer treatment comprising a fluorine compound, a ketone solvent, and a polar aprotic solvent CHRM1, CHRM2, PNMT SLC6A2 728/4885SLC6A3 746/4885SLC6A4 1590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.