SCHEMBL545230

SCHEMBL545230

C=CC(=O)OCO[Si](CCC)(OC)OC

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.44
HPGD P15428 1/20 0.44
ALDH1A1 P00352 4/20 0.37
TP53 P04637 3/20 0.37
HIF1A Q16665 3/20 0.37
CYP3A4 P08684 2/20 0.37
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HSD17B10 Q99714 1/20 0.36
THRB P10828 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27400525 0.90 TSHR (0.50) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL9947748 0.89 TSHR (0.49) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28238283 0.88 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28229095 0.88 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27743751 0.88 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28207620 0.88 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27985885 0.88 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27720138 0.88 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27846911 0.88 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27985914 0.88 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 462 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117801587-B Modified graphene oxide water-based intumescent fireproof coating and preparation method thereof 北京建筑材料科学研究总院有限公司 2026-05-19 CN claimed
EP-4719751-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-04-08 EP claimed
CN-120005322-A High-strength antibacterial polypropylene plastic and preparation method thereof 广东孙小美智能家居科技有限公司 2025-05-16 CN claimed
US-20240399627-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-12-05 US claimed
WO-2024246819-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2024-12-05 WO claimed
CN-118725305-A Photo-curing organic silicon resin and preparation method and application thereof 广东工业大学 2024-10-01 CN claimed
CN-118702979-A Modified nano SiO2Preparation method of basalt fiber reinforced polyolefin composite material 常州瑞杰新材料科技有限公司 2024-09-27 CN claimed
CN-118406431-A Long-chain hyperbranched organosilicon polymer antifouling coating grafted with quaternary ammonium salt and preparation method thereof 中国科学院海洋研究所 2024-07-30 CN claimed
CN-118292274-A Preparation method of non-release type long-acting antibacterial fabric based on polymer/inorganic hybrid nano particles 浙江理工大学 2024-07-05 CN claimed
CN-118255928-A Polymer/inorganic hybrid nano composite particle emulsion, preparation thereof and application thereof in preparation of non-release type durable antibacterial coating 浙江理工大学桐乡研究院有限公司 2024-06-28 CN claimed
EP-0944670-B1 ABRASION-RESISTANT, SILANE-CROSSLINKABLE POLYMER AND POLYMER BLEND COMPOSITIONS DUPONT DOW ELASTOMERS LLC (US) 2003-04-16 EP claimed
US-20030065091-A1 Compatible thermoplastic polyurethane-polyolefin blend compositions DOW GLOBAL TECHNOLOGIES LLC 2003-04-03 US claimed
JP-2002542363-A 2002-12-10 JP claimed
EP-1171525-A1 COMPATIBLE THERMOPLASTIC POLYURETHANE-POLYOLEFIN BLEND COMPOSITIONS DUPONT DOW ELASTOMERS L.L.C. (US) 2002-01-16 EP claimed
WO-2000063293-A1 COMPATIBLE THERMOPLASTIC POLYURETHANE-POLYOLEFIN BLEND COMPOSITIONS DUPONT DOW ELASTOMERS L.L.C. (US) 2000-10-26 WO claimed
EP-0944670-A1 ABRASION-RESISTANT, SILANE-CROSSLINKABLE POLYMER AND POLYMER BLEND COMPOSITIONS DUPONT DOW ELASTOMERS L.L.C. (US) 1999-09-29 EP claimed
WO-1998026001-A1 ABRASION-RESISTANT, SILANE-CROSSLINKABLE POLYMER AND POLYMER BLEND COMPOSITIONS DUPONT DOW ELASTOMERS L.L.C. (US) 1998-06-18 WO claimed
EP-0631598-A4 COMPOSITE DENTAL CEMENT COMPOSITION CONTAINING A LANTHANIDE SERIES COMPOUND. ESSENTIAL DENTAL SYSTEMS INC (US) 1995-04-12 EP claimed
EP-0631598-A1 COMPOSITE DENTAL CEMENT COMPOSITION CONTAINING A LANTHANIDE SERIES COMPOUND ESSENTIAL DENTAL SYSTEMS, INC. (US) 1995-01-04 EP claimed
WO-1993019119-A1 COMPOSITE DENTAL CEMENT COMPOSITION CONTAINING A LANTHANIDE SERIES COMPOUND ESSENTIAL DENTAL SYSTEMS, INC. (US) 1993-09-30 WO claimed