Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 6/20 | 0.37 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5231716 | 0.94 | GPR183 (0.35) | GPR183MEN1KMT2AMAPTNPC1 | |
| SCHEMBL5231720 | 0.94 | GPR183 (0.35) | GPR183MEN1KMT2AMAPTNPC1 | |
| SCHEMBL3236738 | 0.87 | GPR183 (0.44) | GPR183MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL3236746 | 0.87 | GPR183 (0.44) | GPR183MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL3231927 | 0.87 | GPR183 (0.44) | GPR183MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL826353 | 0.87 | GPR183 (0.44) | GPR183MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL826352 | 0.87 | GPR183 (0.44) | GPR183MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL3236172 | 0.87 | NOS2 (0.41) | GPR183BCL2A1NOS2MEN1KMT2A | |
| SCHEMBL3242687 | 0.87 | GPR183 (0.39) | GPR183MEN1KMT2AMAPTNPC1 | |
| SCHEMBL3236465 | 0.87 | NOS2 (0.41) | GPR183BCL2A1NOS2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689706-A4 | ALPHA, BETA-UNSATURATED SULFOXIDES FOR TREATING PROLIFERATIVE DISORDERS | UNIV TEMPLE (US) | 2007-11-14 | — | — | EP | disclosed |
| EP-1689706-A2 | ALPHA, BETA-UNSATURATED SULFOXIDES FOR TREATING PROLIFERATIVE DISORDERS | Temple University of the Commonwealth System of Higher Education (US) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005046599-A2 | ALPHA, BETA-UNSATURATED SULFOXIDES FOR TREATING PROLIFERATIVE DISORDERS | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2005-05-26 | — | — | WO | disclosed |