Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 15/20 | 0.72 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.49 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.49 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.49 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5473916 | 0.90 | ADORA2A (0.59) | ADORA2AADORA1HPGD | |
| SCHEMBL5466032 | 0.88 | ADORA2A (0.74) | ADORA2AADORA1HPGDSLC29A1 | |
| SCHEMBL5461300 | 0.87 | ADORA2A (0.56) | ADORA2AADORA1 | |
| SCHEMBL5451859 | 0.86 | ADORA2A (0.70) | ADORA2AADORA1 | |
| SCHEMBL5462789 | 0.86 | ADORA2A (0.58) | ADORA2AADORA1HPGD | |
| SCHEMBL5460441 | 0.86 | ADORA2A (0.55) | ADORA2AADORA1HPGD | |
| SCHEMBL5460569 | 0.85 | ADORA2A (0.54) | ADORA2AADORA1FGFR1FGFR2FGFR4 | |
| SCHEMBL5466465 | 0.85 | ADORA2A (0.56) | ADORA2AADORA1SLC29A1 | |
| SCHEMBL5454720 | 0.85 | ADORA2A (0.59) | ADORA2AADORA1 | |
| SCHEMBL5456489 | 0.85 | ADORA2A (0.62) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070203159-A1 | Purine compounds | UNIVERSITETET I OLSO (NO) | 2007-08-30 | — | — | US | disclosed |
| US-20070203159-A1 | Purine compounds | UNIVERSITETET I OLSO (NO) | 2007-08-30 | — | — | US | disclosed |
| US-20070203159-A1 | Purine compounds | UNIVERSITETET I OLSO (NO) | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203159-A1 | Purine compounds | PNP, UMPS, TYMP | ADORA2A 96/4885ADORA1 149/4885HPGD 2203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.