SCHEMBL5452946

SCHEMBL5452946

c1ccc(-c2ccnc3c2ccc2c(-c4ccccc4)cc(-c4cccc5ccccc45)nc23)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNF P01375 1/20 0.44
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 2/20 0.40
MAPT P10636 2/20 0.40
HPGD P15428 2/20 0.40
MPI P34949 1/20 0.40
TOP1 P11387 1/20 0.39
CDK5 Q00535 2/20 0.39
ENPP3 O14638 1/20 0.39
ENPP1 P22413 1/20 0.39
PLG P00747 1/20 0.39
GSK3B P49841 1/20 0.39
CDK5R1 Q15078 1/20 0.39
TP53 P04637 1/20 0.38
TSHR P16473 1/20 0.38
NFKB1 P19838 1/20 0.38
MAPK1 P28482 1/20 0.38
NFKB2 Q00653 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14581506 0.96 TOP1 (0.42) TNFTOP1CDK5PLGMAPK1
SCHEMBL5463115 0.92 TOP1 (0.39) TNFTOP1CDK5PLGMAPK1
SCHEMBL3697659 0.90 MEN1 (0.49) TNFMEN1KMT2AKDM4EALDH1A1
SCHEMBL5456861 0.88 TOP1 (0.43) TNFMEN1KMT2AKDM4EALDH1A1
SCHEMBL14581505 0.88 CCR1 (0.41) TNFMEN1KMT2AKDM4EALDH1A1
SCHEMBL13458738 0.87 MEN1 (0.47) TNFMEN1KMT2AKDM4EALDH1A1
SCHEMBL440428 0.87 MEN1 (0.47) TNFMEN1KMT2AKDM4EALDH1A1
SCHEMBL28106850 0.86 TOP1 (0.39) TNFKDM4EALDH1A1MAPTHPGD
SCHEMBL1543078 0.86 CYP11B1 (0.50) TNFMEN1KMT2AKDM4EALDH1A1
SCHEMBL5457475 0.86 CCR1 (0.40) TNFMEN1KMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117858868-A Organometallic compound for protective layer, method for processing organic semiconductor layer, and method for manufacturing organic semiconductor device 株式会社半导体能源研究所 2024-04-09 CN disclosed
CN-117223394-A Display device and electronic apparatus 株式会社半导体能源研究所 2023-12-12 CN disclosed
CN-116589497-A Indolocarbazole compound containing silane and organic electroluminescent device thereof 长春海谱润斯科技股份有限公司 2023-08-15 CN disclosed
CN-112186112-A Material for hole transport layer, material for hole injection layer, and organic compound 株式会社半导体能源研究所 2021-01-05 CN disclosed
US-9088002-B2 Light-emitting device and manufacturing method thereof SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-07-21 US disclosed
US-20120205633-A1 Light-Emitting Device and Manufacturing Method Thereof SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-08-16 US disclosed
US-20100288362-A1 INTERNAL CONNECTOR FOR ORGANIC ELECTRONIC DEVICES GLOBAL OLED TECHNOLOGY LLC 2010-11-18 US disclosed
US-20100288362-A1 INTERNAL CONNECTOR FOR ORGANIC ELECTRONIC DEVICES GLOBAL OLED TECHNOLOGY LLC 2010-11-18 US disclosed
US-20100026176-A1 Transparent, Thermally Stable Light-Emitting Component Having Organic Layers NOVALED AG (DE) 2010-02-04 US disclosed
US-20100026176-A1 Transparent, Thermally Stable Light-Emitting Component Having Organic Layers NOVALED AG (DE) 2010-02-04 US disclosed
US-20070037983-A1 Phenanthroline derivative compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-02-15 US disclosed
US-20070037983-A1 Phenanthroline derivative compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-02-15 US disclosed
US-20070037983-A1 Phenanthroline derivative compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070037983-A1 Phenanthroline derivative compound POP1, PABPC1, NAP1L1 TNF 4499/4885MEN1 3391/4885KMT2A 3592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.