SCHEMBL545299

SCHEMBL545299

CCO[Si](OCC)(OCC)c1ccc(-c2ccc([Si](OCC)(OCC)OCC)cc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.34
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
XDH P47989 1/20 0.32
NQO1 P15559 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30
HSD17B10 Q99714 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13933201 1.00 ESR1 (0.34) ESR1CYP3A4CYP2D6XDHNQO1
SCHEMBL14429555 1.00 ESR1 (0.34) ESR1CYP3A4CYP2D6XDHNQO1
SCHEMBL544954 0.95 ESR1 (0.32) ESR1CYP3A4CYP2D6XDH
SCHEMBL50701 0.92 NQO1 (0.35) ESR1NQO1
SCHEMBL20478197 0.92 NQO1 (0.35) ESR1NQO1
SCHEMBL2777619 0.91 SMN1; SMN2 (0.40) KDM4EALDH1A1MAPTHPGDMAPK1
SCHEMBL14267362 0.91 TARBP2 (0.35) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL14264690 0.91 SMN1; SMN2 (0.40) KDM4EALDH1A1MAPTHPGDMAPK1
SCHEMBL17618923 0.91 TARBP2 (0.35) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL15736123 0.89 NPC1 (0.37) CYP2D6KDM4EMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304819-A1 Flexible and foldable abrasion resistant photopatternable siloxane hard coat OPTITUNE OY (FI) 2025-10-02 US claimed
EP-4569015-A1 BIOCOMPATIBLE OXYGEN-SENSITIVE MATERIALS Promega Corporation (US) 2025-06-18 EP claimed
CN-115786896-B Environment-friendly passivation solution for galvanized aluminum magnesium plate and preparation method thereof 上海兴赛尔表面材料有限公司 2025-03-14 CN claimed
US-12102985-B2 Metal particle-loaded hollow mesoporous organosilica nano/microparticles and method for manufacturing same PUSAN NATIONAL UNIVERSITY INDUSTRY UNIVERSITY COOPERATION FOUNDATION (KR) 2024-10-01 US claimed
US-20240299314-A1 DRUG DELIVERING NANO DEVICES AND METHODS OF SYNTHESIZING AND CURING CANCERS USING THE SAME VIETNAM NATIONAL UNIVERSITY HO CHI MINH CITY (VN) 2024-09-12 US claimed
CN-114733374-B Organic silicon film for biphenyl bridge, preparation method and application 常州大学 2024-04-05 CN claimed
CN-107636097-B Silicone polymer composition and use thereof 奥普提汀公司 2024-03-15 CN claimed
US-20240059961-A1 BIOCOMPATIBLE OXYGEN-SENSITIVE MATERIALS PROMEGA CORPORATION 2024-02-22 US claimed
WO-2024036277-A1 BIOCOMPATIBLE OXYGEN-SENSITIVE MATERIALS PROMEGA CORPORATION (US) 2024-02-15 WO claimed
CN-117463173-A MOF-74/biphenyl bridge organic silicon hybrid film and preparation method and application thereof 常州大学 2024-01-30 CN claimed
US-20220010172-A1 SILOXANE POLYMER COMPOSITIONS AND THEIR USE OPTITUNE OY (FI) 2022-01-13 US claimed
US-11127864-B2 Carbosiloxane polymer compositions, methods of producing the same and the use thereof OPTITUNE OY (FI) 2021-09-21 US claimed
US-20210087429-A1 Flexible and foldable abrasion resistant photopatternable siloxane hard coat OPTITUNE OY (FI) 2021-03-25 US claimed
US-20180066159-A1 SILOXANE POLYMER COMPOSITIONS AND THEIR USE BASF SE (DE) 2018-03-08 US claimed
EP-3271433-A1 NOVEL SILOXANE POLYMER COMPOSITIONS AND THEIR USE BASF SE (DE) 2018-01-24 EP claimed
WO-2016146896-A1 NOVEL SILOXANE POLYMER COMPOSITIONS AND THEIR USE OPTITUNE OY (FI) 2016-09-22 WO claimed
EP-2054344-B1 ORGANIC-INORGANIC HYBRID SILICATES AND METAL-SILICATES HAVING AN ORDERED STRUCTURE ENI SPA (IT) 2011-03-16 EP claimed
US-20100178468-A1 ULTRA-THIN MICROPOROUS/HYBRID MATERIALS UNITED STATES DEPARTMENT OF ENERGY 2010-07-15 US claimed
WO-2009102363-A2 ULTRA-THIN MICROPOROUS/HYBRID MATERIALS STC.UNM (US) 2009-08-20 WO claimed
EP-1995214-A2 Multifunctional periodic mesoporous organosilica materials using block copolymer template and preparation method thereof Sungkyunkwan University Foundation for Corporate Collaboration (KR) 2008-11-26 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240059961-A1 BIOCOMPATIBLE OXYGEN-SENSITIVE MATERIALS COXFA4L2, LOXL1, LOX ESR1 1005/4885CYP3A4 1045/4885CYP2D6 1962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.