Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL423414 | 0.73 | TAAR1 (0.50) | CYP1A2CYP2C9CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL3003528 | 0.71 | TAAR1 (0.48) | CYP1A2CYP2C9CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL27616376 | 0.71 | HTT (0.54) | CYP1A2CYP2C9CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL11195639 | 0.70 | TAAR1 (0.50) | CYP1A2CYP2C9CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL27604357 | 0.68 | TAAR1 (0.50) | TAAR1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL12463715 | 0.67 | TAAR1 (0.48) | CYP1A2CYP2C9CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL14387546 | 0.67 | TAAR1 (0.48) | TAAR1MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL5461597 | 0.67 | ROCK1 (0.40) | HTTTAAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL10387393 | 0.66 | MEN1 (0.43) | CYP1A2CYP2C9CYP2C19HTTTAAR1 | |
| SCHEMBL8155665 | 0.66 | TAAR1 (0.41) | CYP1A2CYP2C9CYP2C19HTTTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070093531-A1 | Novel hydroxyindoles, their use as inhibitors of phosphodiesterase 4, and processes for preparing them | ELBION AG | 2007-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070093531-A1 | Novel hydroxyindoles, their use as inhibitors of phosphodiesterase 4, and processes for preparing them | PDE4B, PDE4A, PDE4D | CYP1A2 230/4885CYP2C9 418/4885CYP2C19 169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.