Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10820270 | 0.83 | CES2 (0.36) | ALDH1A1 | |
| SCHEMBL21519520 | 0.83 | CYP1A2 (0.43) | TAAR1MEN1KMT2ACYP1A2TDP1 | |
| SCHEMBL10387393 | 0.77 | MEN1 (0.43) | TAAR1MEN1KMT2AGAACYP1A2 | |
| SCHEMBL29812934 | 0.77 | GABRA1 (0.46) | TAAR1MEN1KMT2AGAACYP1A2 | |
| SCHEMBL158972 | 0.77 | GABRA1 (0.46) | TAAR1MEN1KMT2AGAACYP1A2 | |
| SCHEMBL1950281 | 0.72 | GABRA1 (0.47) | TAAR1MEN1KMT2AGAACYP1A2 | |
| SCHEMBL29648809 | 0.72 | GABRA1 (0.47) | TAAR1MEN1KMT2AGAACYP1A2 | |
| SCHEMBL11884432 | 0.72 | HTR3E (0.48) | TAAR1MEN1KMT2AGAACYP2C9 | |
| SCHEMBL8097830 | 0.72 | TAAR1 (0.37) | TAAR1MEN1KMT2AGAACYP1A2 | |
| SCHEMBL27214923 | 0.70 | MEN1 (0.44) | TAAR1MEN1KMT2AGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888297-B1 | N-ARYLSULFILIMINE COMPOUNDS AND THEIR USE AS CATALYSTS IN THE PREPARATION OF N-ARYLARYLSULFONAMIDE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2000-08-30 | — | — | EP | disclosed |