Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5456248 | 0.88 | MEN1 (0.42) | MEN1KMT2AMAPTL3MBTL1POLB | |
| SCHEMBL5456538 | 0.79 | NPC1 (0.67) | MEN1KMT2AMAPTL3MBTL1POLB | |
| SCHEMBL5451682 | 0.71 | ALDH1A1 (0.64) | MEN1KMT2AMAPTL3MBTL1POLB | |
| SCHEMBL5458578 | 0.69 | POLB (0.74) | MEN1KMT2AMAPTL3MBTL1POLB | |
| SCHEMBL6901966 | 0.69 | ALDH1A1 (0.61) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL4665324 | 0.69 | MEN1 (0.64) | MEN1KMT2AMAPTL3MBTL1POLB | |
| SCHEMBL11899820 | 0.68 | MEN1 (0.41) | MEN1KMT2ARAB9AKDM4EALDH1A1 | |
| SCHEMBL5458059 | 0.68 | ALDH1A1 (0.61) | MEN1KMT2AMAPTL3MBTL1POLB | |
| SCHEMBL18205210 | 0.67 | MEN1 (0.58) | MEN1KMT2AMAPTL3MBTL1POLB | |
| SCHEMBL12226492 | 0.67 | MEN1 (0.61) | MEN1KMT2AMAPTL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043024-A1 | Azacyclic compounds as inhibitors of sensory neurone specific channels | IONIX PHARMACEUTICALS LIMITED (GB) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043024-A1 | Azacyclic compounds as inhibitors of sensory neurone specific channels | SCN1B, SCN1A, SCN10A | MEN1 2444/4885KMT2A 2911/4885MAPT 2361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.