Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.53 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.51 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | AIP | O00170 | 1/20 | 0.49 |
| ▸ | SGTA | O43765 | 1/20 | 0.49 |
| ▸ | TOMM70 | O94826 | 1/20 | 0.49 |
| ▸ | STIP1 | P31948 | 1/20 | 0.49 |
| ▸ | PPP5C | P53041 | 1/20 | 0.49 |
| ▸ | DNAJC7 | Q99615 | 1/20 | 0.49 |
| ▸ | STUB1 | Q9UNE7 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5462746 | 0.88 | MAPT (0.69) | MAPTDUSP3PTPN5PTPN11ANO1 | |
| SCHEMBL8290431 | 0.85 | ANO1 (0.72) | MAPTDUSP3PTPN5PTPN11ANO1 | |
| SCHEMBL5449286 | 0.83 | PTPN1 (0.55) | PTPN1MAPTDUSP3PTPN5PTPN11 | |
| SCHEMBL5454129 | 0.82 | PTPN1 (0.52) | PTPN1MAPTDUSP3PTPN5PTPN11 | |
| SCHEMBL8289710 | 0.82 | KDM4E (0.70) | MAPTANO1ALDH1A1NPC1RAB9A | |
| SCHEMBL5459748 | 0.82 | FLT3 (0.70) | MAPTANO1ALDH1A1NPC1RAB9A | |
| SCHEMBL5446191 | 0.82 | TNIK (0.59) | PTPN1MAPTDUSP3PTPN5PTPN11 | |
| SCHEMBL8290436 | 0.81 | FLT3 (0.68) | MAPTANO1ALDH1A1NPC1RAB9A | |
| SCHEMBL5455042 | 0.80 | FLT3 (0.70) | PTPN1MAPTDUSP3PTPN5PTPN11 | |
| SCHEMBL5451302 | 0.80 | FLT3 (0.70) | PTPN1MAPTDUSP3PTPN5PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | claimed |
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | TBCA, PARK7, NFATC1 | PTPN1 2192/4885MAPT 21/4885DUSP3 110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.