Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | USP2 | O75604 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 2/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170859 | 0.83 | KDM4E (0.54) | GAAMAPTKDM4EHTTMAPK1 | |
| SCHEMBL10188105 | 0.81 | GAA (0.69) | GAAMAPTKDM4EHTTMAPK1 | |
| SCHEMBL11703261 | 0.80 | GAA (0.62) | GAAMAPTKDM4EHTTMAPK1 | |
| SCHEMBL30336546 | 0.80 | GAA (0.67) | GAAMAPTKDM4EHTTMAPK1 | |
| SCHEMBL25193781 | 0.80 | GAA (0.67) | GAAMAPTKDM4EHTTMAPK1 | |
| SCHEMBL10187277 | 0.80 | MAPT (0.66) | GAAMAPTKDM4EHTTMAPK1 | |
| SCHEMBL10187284 | 0.80 | GAA (0.71) | GAAMAPTKDM4EHTTMAPK1 | |
| SCHEMBL11341850 | 0.79 | GAA (0.65) | GAAMAPTKDM4EHTTMAPK1 | |
| SCHEMBL7920252 | 0.79 | GAA (0.65) | GAAMAPTKDM4EHTTMAPK1 | |
| SCHEMBL7906785 | 0.79 | GAA (0.65) | GAAMAPTKDM4EHTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007061966-A2 | AMIDINYLPHENYL COMPOUNDS AND THEIR USE AS FUNGICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-05-31 | — | — | WO | disclosed |