Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5455571 | 0.82 | NPSR1 (0.42) | HCAR2ALDH1A1TSHRNPSR1SMN1; SMN2 | |
| SCHEMBL16160127 | 0.79 | ATM (0.48) | HCAR2ATMALDH1A1TSHRHPGD | |
| SCHEMBL4437232 | 0.77 | HCAR2 (0.53) | HCAR2ATMALDH1A1TSHRHPGD | |
| SCHEMBL4437235 | 0.77 | HCAR2 (0.53) | HCAR2ATMALDH1A1TSHRHPGD | |
| SCHEMBL27817802 | 0.76 | ATM (0.46) | HCAR2ATMALDH1A1TSHRHPGD | |
| SCHEMBL28065386 | 0.76 | ATM (0.46) | HCAR2ATMALDH1A1TSHRHPGD | |
| SCHEMBL598743 | 0.75 | ALDH1A1 (0.52) | HCAR2ATMALDH1A1TSHRHPGD | |
| SCHEMBL7767048 | 0.75 | ALDH1A1 (0.52) | HCAR2ATMALDH1A1TSHRHPGD | |
| SCHEMBL598745 | 0.75 | ALDH1A1 (0.52) | HCAR2ATMALDH1A1TSHRHPGD | |
| SCHEMBL27395298 | 0.75 | HCAR2 (0.44) | HCAR2ATMALDH1A1TSHRNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043205-A1 | Radiation curable thiol-ene composition | DSM IP ASSETS B.V. (NL) | 2007-02-22 | — | — | US | disclosed |
| EP-1477511-A1 | Radiation curable thiol-ene composition | DSM IP Assets B.V. (NL) | 2004-11-17 | — | — | EP | disclosed |