SCHEMBL5453949

SCHEMBL5453949

Brc1ccc([NH+](c2ccc(Br)cc2)c2ccc(Br)cc2)cc1.Fc1c(F)c(F)c([B-](c2c(F)c(F)c(F)c(F)c2F)(c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2F)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.33
ALDH1A1 P00352 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1135161 0.84 CYP2A6 (0.31) CYP2A6ALDH1A1
SCHEMBL199904 0.78
4-Bromoaniline SCHEMBL6903090 0.77 CYP2A6 (0.35) CYP2A6ALDH1A1MAPK1
SCHEMBL20350780 0.72 CYP2A6 (0.44) CYP2A6ALDH1A1MAPK1
SCHEMBL3919371 0.71 ALDH1A1 (0.40) ALDH1A1MAPK1
SCHEMBL22478 0.68
SCHEMBL8591536 0.68
SCHEMBL22462009 0.67 CYP2A6 (0.44) CYP2A6ALDH1A1MAPK1
SCHEMBL25231433 0.66
Benzene SCHEMBL28592113 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070020479-A1 Luminescent-polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-01-25 US disclosed