Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 12/20 | 0.50 |
| ▸ | MAOB | P27338 | 10/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.50 |
| ▸ | DPP4 | P27487 | 3/20 | 0.50 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 7/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5454146 | 1.00 | KDM1A (0.50) | KDM1AMAOBKCNH2RCOR1DPP4 | |
| SCHEMBL5454149 | 1.00 | KDM1A (0.50) | KDM1AMAOBKCNH2RCOR1DPP4 | |
| SCHEMBL5188216 | 0.75 | CYP2C9 (0.40) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL5188204 | 0.75 | CYP2C9 (0.40) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL5188210 | 0.75 | CYP2C9 (0.40) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL5188052 | 0.74 | RORC (0.68) | KDM1AMAOBKCNH2RCOR1DPP4 | |
| SCHEMBL5188039 | 0.74 | RORC (0.68) | KDM1AMAOBKCNH2RCOR1DPP4 | |
| SCHEMBL5188045 | 0.74 | RORC (0.68) | KDM1AMAOBKCNH2RCOR1DPP4 | |
| SCHEMBL5186751 | 0.73 | KDM1A (0.53) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL5186738 | 0.73 | KDM1A (0.53) | KDM1AMAOBKCNH2RCOR1KDM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070270471-A1 | Compounds Which Potentiate Glutamate Receptor and Uses Thereof in Medicine | GLAXO GROUP LIMITED (GB) | 2007-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270471-A1 | Compounds Which Potentiate Glutamate Receptor and Uses Thereof in Medicine | GRM3, GLRA3, GLRA1 | KDM1A 3089/4885MAOB 1272/4885KCNH2 562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.