Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5449730 | 0.89 | DPP4 (0.39) | ALDH1A1LMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL5449869 | 0.89 | ALDH1A1 (0.37) | ALDH1A1LMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL5452381 | 0.87 | KDM4E (0.39) | ALDH1A1LMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5451700 | 0.85 | NR3C2 (0.39) | ALDH1A1LMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4124732 | 0.85 | NR3C2 (0.47) | ALDH1A1LMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL5442885 | 0.85 | NR3C2 (0.38) | ALDH1A1LMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5449319 | 0.82 | NR3C2 (0.38) | ALDH1A1LMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL5455219 | 0.81 | NR3C2 (0.42) | ALDH1A1LMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL5447730 | 0.80 | KDM4E (0.49) | ALDH1A1LMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL5449799 | 0.78 | NR3C2 (0.40) | ALDH1A1LMNASMN1; SMN2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037807-A1 | Pyridine compounds as inhibitors of dipeptidyl peptidase IV | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037807-A1 | Pyridine compounds as inhibitors of dipeptidyl peptidase IV | DPP4, DPP3, PEPD | ALDH1A1 743/4885LMNA 2641/4885SMN1; SMN2 4203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.