SCHEMBL5454444

SCHEMBL5454444

CCO[Si](OCC)(OCC)C(OCC1CO1)C(C)CC

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TDP1 Q9NUW8 1/20 0.31
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28739265 0.89 SMN1; SMN2 (0.32) ALDH1A1SMN1; SMN2TDP1
SCHEMBL5363753 0.88 SMN1; SMN2 (0.38) ALDH1A1SMN1; SMN2TDP1TSHR
SCHEMBL5379300 0.87 SMN1; SMN2 (0.34) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL5379297 0.85 ALDH1A1 (0.34) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL5360976 0.85 SMN1; SMN2 (0.46) ALDH1A1SMN1; SMN2TDP1TSHR
SCHEMBL14743131 0.81 SMN1; SMN2 (0.31) ALDH1A1SMN1; SMN2
SCHEMBL188051 0.80 SMN1; SMN2 (0.36) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL16430090 0.78 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL143619 0.78 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL5598865 0.77 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070251448-A1 Application method, applicator, optical member, and optical device SAKURADA KAZUAKI 2007-11-01 US disclosed
CN-1310706-C Coating method, coating device, optical component and optical device SEIKO EPSON CORP (JP) 2007-04-18 CN disclosed
US-6773465-B1 Optical element ITOH OPTICAL INDUSTRIAL CO., LTD. (JP) 2004-08-10 US disclosed
CN-1478608-A Coating method, coating device, optical component and optical device ������������ʽ���� 2004-03-03 CN disclosed
US-4294950-A POLYVALENT CARBOXYLIC ACID BONDED THERETO ITO OPTICAL INDUSTRIAL CO., LTD. (JP) 1981-10-13 US disclosed