Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 15/20 | 0.49 |
| ▸ | EGLN1 | Q9GZT9 | 14/20 | 0.49 |
| ▸ | THRA | P10827 | 5/20 | 0.48 |
| ▸ | THRB | P10828 | 5/20 | 0.48 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | ASPH | Q12797 | 1/20 | 0.46 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5380536 | 1.00 | EGLN2 (0.49) | EGLN2EGLN1THRATHRBBBOX1 | |
| SCHEMBL5454614 | 1.00 | EGLN2 (0.49) | EGLN2EGLN1THRATHRBBBOX1 | |
| SCHEMBL523581 | 0.82 | EGLN2 (0.58) | EGLN2EGLN1THRATHRB | |
| SCHEMBL522868 | 0.82 | EGLN2 (0.58) | EGLN2EGLN1THRATHRB | |
| SCHEMBL522869 | 0.82 | EGLN2 (0.58) | EGLN2EGLN1THRATHRB | |
| SCHEMBL13601811 | 0.82 | THRA (0.52) | EGLN2EGLN1THRATHRBBBOX1 | |
| SCHEMBL526495 | 0.81 | EGLN2 (0.57) | EGLN2EGLN1THRATHRB | |
| SCHEMBL522066 | 0.78 | THRA (0.77) | EGLN1THRATHRBBBOX1SLC6A2 | |
| SCHEMBL523667 | 0.76 | EGLN2 (0.54) | EGLN2EGLN1THRATHRB | |
| SCHEMBL523668 | 0.76 | EGLN2 (0.54) | EGLN2EGLN1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047194-A2 | METHODS FOR TREATING MITF-RELATED DISORDERS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |