Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 12/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5456961 | 0.90 | DPP4 (0.48) | ALDH1A1L3MBTL1DPP4DPP8DPP9 | |
| SCHEMBL5449831 | 0.88 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1DPP4DPP8DPP9 | |
| SCHEMBL5451593 | 0.88 | DPP4 (0.42) | ALDH1A1L3MBTL1DPP4DPP8DPP9 | |
| SCHEMBL5457960 | 0.87 | DPP4 (0.52) | ALDH1A1L3MBTL1DPP4DPP8DPP9 | |
| SCHEMBL5441393 | 0.86 | DPP4 (0.41) | ALDH1A1L3MBTL1DPP4DPP8DPP9 | |
| SCHEMBL5457196 | 0.83 | DPP4 (0.59) | DPP4DPP8DPP9 | |
| SCHEMBL5442732 | 0.83 | DPP4 (0.47) | ALDH1A1DPP4DPP8DPP9KDM4E | |
| SCHEMBL5447534 | 0.82 | PTPN1 (0.43) | ALDH1A1L3MBTL1DPP4DPP8KDM4E | |
| SCHEMBL5463607 | 0.80 | DPP4 (0.43) | ALDH1A1DPP4DPP8DPP9KDM4E | |
| SCHEMBL5462030 | 0.80 | KMT2A (0.41) | ALDH1A1L3MBTL1DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037807-A1 | Pyridine compounds as inhibitors of dipeptidyl peptidase IV | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037807-A1 | Pyridine compounds as inhibitors of dipeptidyl peptidase IV | DPP4, DPP3, PEPD | ALDH1A1 743/4885L3MBTL1 473/4885DPP4 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.