SCHEMBL5455050

SCHEMBL5455050

S=C(Nc1ccccc1)NC1CCCCC1

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 11/20 0.88
LMNA P02545 7/20 0.88
MAPT P10636 4/20 0.88
MEN1 O00255 3/20 0.88
KMT2A Q03164 3/20 0.88
GAA P10253 1/20 0.88
MAPK1 P28482 1/20 0.88
TDP1 Q9NUW8 1/20 0.88
ALOX12 P18054 5/20 0.75
HTT P42858 4/20 0.75
ALDH1A1 P00352 3/20 0.75
TP53 P04637 1/20 0.75
NPSR1 Q6W5P4 1/20 0.71
RAB9A P51151 4/20 0.68
NPC1 O15118 3/20 0.68
CYP1A2 P05177 2/20 0.68
CYP3A4 P08684 2/20 0.68
CYP2C19 P33261 2/20 0.68
POLB P06746 1/20 0.68
CYP2D6 P10635 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5447885 0.98 SMN1; SMN2 (0.84) SMN1; SMN2LMNAMAPTMEN1KMT2A
Tetramethylammonium Ion SCHEMBL28520218 0.94 SMN1; SMN2 (0.78) SMN1; SMN2LMNAMAPTMEN1KMT2A
SCHEMBL11284872 0.91 SMN1; SMN2 (0.73) SMN1; SMN2LMNAMAPTMEN1KMT2A
SCHEMBL28756963 0.91 SMN1; SMN2 (0.83) SMN1; SMN2LMNAMAPTMEN1KMT2A
SCHEMBL28033892 0.84 SMN1; SMN2 (0.64) SMN1; SMN2LMNAMAPTMEN1KMT2A
SCHEMBL11697622 0.83 NPSR1 (1.00) SMN1; SMN2LMNAMAPTMEN1KMT2A
SCHEMBL3876288 0.83 SMN1; SMN2 (0.71) SMN1; SMN2LMNAMAPTMEN1KMT2A
SCHEMBL11149053 0.83 SMN1; SMN2 (0.97) SMN1; SMN2LMNAMAPTMEN1KMT2A
SCHEMBL23453329 0.81 SMN1; SMN2 (0.69) SMN1; SMN2LMNAMAPTMEN1KMT2A
SCHEMBL26123831 0.81 MEN1 (1.00) SMN1; SMN2LMNAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117619331-A Production process and device for synthesizing methyl tetrahydrophthalic anhydride from diene 浙江正大新材料科技股份有限公司 2024-03-01 CN claimed
CN-115073736-B Catalytic method for controllable copolymerization of epoxy and isothiocyanate 华南理工大学 2023-08-22 CN claimed
CN-115073736-A Catalytic method for controllable copolymerization of epoxy and isothiocyanate 华南理工大学 2022-09-20 CN claimed
WO-2022188406-A1 CATALYTIC METHOD FOR CONTROLLABLE COPOLYMERIZATION OF EPOXY AND ISOTHIOCYANATE 华南理工大学 2022-09-15 WO claimed
US-11286341-B2 Ring-opening polymerizations using a flow reactor INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2022-03-29 US claimed
US-20200407496-A1 RING-OPENING POLYMERIZATIONS USING A FLOW REACTOR INTERNATIONAL BUSINESS MACHINES CORPORATION 2020-12-31 US claimed
CN-119841777-A Synthesis method and application of C2-substituted dihydroquinoline derivative 南京林业大学 2025-04-18 CN disclosed
CN-119585827-A Laminated ceramic electronic component precursor and laminated ceramic electronic component manufacturing method 株式会社村田制作所 2025-03-07 CN disclosed
CN-118184973-A Multifunctional CO2Base copolyester and preparation method thereof 青岛科技大学 2024-06-14 CN disclosed
CN-118184972-A CO with side chain containing two double bond functional groups2Base polyester and preparation method thereof 青岛科技大学 2024-06-14 CN disclosed
CN-117619331-A Production process and device for synthesizing methyl tetrahydrophthalic anhydride from diene 浙江正大新材料科技股份有限公司 2024-03-01 CN disclosed
WO-2024029328-A1 MULTILAYER CERAMIC ELECTRONIC COMPONENT PRECURSOR AND METHOD FOR PRODUCING MULTILAYER CERAMIC ELECTRONIC COMPONENT 株式会社村田製作所 2024-02-08 WO disclosed
CN-116783070-A Composite structure, laminated ceramic electronic component precursor, method for producing laminated ceramic electronic component precursor, and method for producing laminated ceramic electronic component 株式会社村田制作所 2023-09-19 CN disclosed
CN-1229360-C Preparation method of 2-(hydrocarbon) imido (amine)-4-thiazolidone UNIV CHINA PHARMA (CN) 2005-11-30 CN disclosed
CN-1229361-C Preparation method of 2-(hydrocarbon) imido (amine)-4-thiazolidone hydrochloride UNIV CHINA PHARMA (CN) 2005-11-30 CN disclosed
CN-1556107-A Preparation method of 2-(hydrocarbon) imido (amine)-4-thiazolidone hydrochloride 中国药科大学 2004-12-22 CN disclosed
CN-1556106-A Preparation method of 2-(hydrocarbon) imido (amine)-4-thiazolidone 中国药科大学 2004-12-22 CN disclosed
US-4921939-A GUANIDINE AND AMIDINE COMPOUNDS CONTAINING ACID GROUPS UNIVERSITE CLAUDE BERNARD -LYON 1 (FR) 1990-05-01 US disclosed
EP-0241395-A2 Sweeteners derived from n-phenylguanidinoacetic and n-phenylethananamidinacetic acids, and compositions containing such sweeteners UNIVERSITE CLAUDE BERNARD - LYON 1 (FR) 1987-10-14 EP disclosed
US-4252963-A CYCLIZATION OF PHENYLTHIOUREAS WITH THIONYL CHLORIDE HOECHST AKTIENGESELLSCHAFT (DE) 1981-02-24 US disclosed