Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.63 |
| ▸ | CLK2 | P49760 | 1/20 | 0.63 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | GSK3B | P49841 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TOP2A | P11388 | 6/20 | 0.58 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL483223 | 0.98 | KDM4E (0.65) | KDM4EHPGDKCNH2ALDH1A1HSD17B10 | |
| SCHEMBL29393776 | 0.98 | KDM4E (0.65) | KDM4EHPGDKCNH2ALDH1A1HSD17B10 | |
| SCHEMBL541514 | 0.97 | KDM4E (0.64) | KDM4EHPGDKCNH2ALDH1A1HSD17B10 | |
| SCHEMBL28424222 | 0.97 | KDM4E (0.64) | KDM4EHPGDKCNH2ALDH1A1HSD17B10 | |
| SCHEMBL541515 | 0.97 | KDM4E (0.64) | KDM4EHPGDKCNH2ALDH1A1HSD17B10 | |
| Fluoride SCHEMBL5143207 | 0.96 | KDM4E (0.63) | KDM4EHPGDKCNH2ALDH1A1HSD17B10 | |
| Boric Acid SCHEMBL1155094 | 0.94 | KDM4E (0.62) | KDM4EHPGDKCNH2ALDH1A1HSD17B10 | |
| SCHEMBL3558935 | 0.94 | KDM4E (0.62) | KDM4EHPGDKCNH2ALDH1A1HSD17B10 | |
| SCHEMBL4368210 | 0.94 | KDM4E (0.62) | KDM4EHPGDKCNH2ALDH1A1HSD17B10 | |
| SCHEMBL12427273 | 0.93 | KCNH2 (0.60) | KDM4EHPGDKCNH2ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275994-A1 | Novel Antinfective Compounds | CADILA HEALTHCARE LIMITED (IN) | 2007-11-29 | — | — | US | disclosed |
| WO-2005019224-A2 | NOVEL ANTIINFECTIVE COMPOUNDS | CADILA HEALTHCARE LIMITED (IN) | 2005-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275994-A1 | Novel Antinfective Compounds | VIP, MPO, FABP2 | KDM4E 3420/4885HPGD 810/4885KCNH2 801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.