⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1276262 | 0.85 | ALDH1A1 (0.56) | — | |
| SCHEMBL14192214 | 0.85 | KDM4E (0.45) | — | |
| SCHEMBL6009315 | 0.84 | — | — | |
| SCHEMBL11817859 | 0.82 | EPHX1 (0.48) | — | |
| SCHEMBL24285431 | 0.80 | EPHX1 (0.52) | — | |
| SCHEMBL9666793 | 0.80 | EPHX1 (0.52) | — | |
| SCHEMBL6398229 | 0.80 | EPHX1 (0.52) | — | |
| SCHEMBL17511736 | 0.80 | EPHX1 (0.52) | — | |
| SCHEMBL17037351 | 0.78 | — | — | |
| SCHEMBL16372492 | 0.78 | QPCT (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110546566-B | Positive photosensitive siloxane composition and cured film formed using same | 默克专利有限公司 | 2024-02-09 | — | — | CN | disclosed |
| US-11860537-B2 | Positive type photosensitive siloxane composition and cured film formed by using the same | MERCK PATENT GMBH (DE) | 2024-01-02 | — | — | US | disclosed |
| US-20230202977-A1 | CYCLIC LIPIDS AND METHODS OF USE THEREOF | RENAGADE THERAPEUTICS MANAGEMENT INC. | 2023-06-29 | — | — | US | disclosed |
| CN-114106475-A | Rubber composition for sealing material, and pneumatic tire | 住友橡胶工业株式会社 | 2022-03-01 | — | — | CN | disclosed |
| US-20210116811-A1 | POSITIVE TYPE PHOTOSENSITIVE SILOXANE COMPOSITION AND CURED FILM FORMED BY USING THE SAME | MERCK PATENT GMBH (DE) | 2021-04-22 | — | — | US | disclosed |
| CN-110546566-A | Positive photosensitive siloxane composition and cured film formed using same | MERCK PATENT GMBH | 2019-12-06 | — | — | CN | disclosed |
| US-20170027919-A1 | Method for the Treatment of Neurological Disorders by Enhancing the Activity of Beta-Glucocerebrosidase | AMICUS THERAPEUTICS INC (US) | 2017-02-02 | — | — | US | disclosed |
| WO-2016167511-A2 | N2-(2-METHOXYPHENYL)PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR CANCER PREVENTION OR TREATMENT CONTAINING SAME AS ACTIVE INGREDIENT | 한국화학연구원 | 2016-10-20 | — | — | WO | disclosed |
| US-9402837-B2 | Method for the treatment of neurological disorders by enhancing the activity of β-glucocerebrosidase | AMICUS THERAPEUTICS, INC. (US) | 2016-08-02 | — | — | US | disclosed |
| US-9119845-B2 | Method for the treatment of neurological disorders by enhancing the activity of beta-glucocerebrosidase | Amicus Therapeautics, Inc. (US) | 2015-09-01 | — | — | US | disclosed |
| US-20110262357-A1 | Metalloporphyrin Derivatives, Nanoparticles Comprising the Same, and Use Thereof for Photodynamic Therapy | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2011-10-27 | — | — | US | disclosed |
| US-20110262357-A1 | Metalloporphyrin Derivatives, Nanoparticles Comprising the Same, and Use Thereof for Photodynamic Therapy | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2011-10-27 | — | — | US | disclosed |
| US-20110190278-A1 | BICYCLIC HETEROCYCLIC DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO. | 2011-08-04 | — | — | US | disclosed |
| EP-2243779-A1 | BICYCLIC HETEROCYCLIC DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2010-10-27 | — | — | EP | disclosed |
| US-20100056507-A1 | PHENYL DERIVATIVES AND THEIR USE AS A MEDICAMENT | IPSEN PHARMA S.A.S. (FR) | 2010-03-04 | — | — | US | disclosed |
| US-7342012-B2 | Inhibitors of αLβ2 mediated cell adhesion | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-03-11 | — | — | US | disclosed |
| US-7342012-B2 | Inhibitors of αLβ2 mediated cell adhesion | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-03-11 | — | — | US | disclosed |
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |
| US-5246688-A | Heating aqueous homogeneous reaction mixture comprising fluosilicate, reagent providing hydroxide ions by hydrothermal decomposition, structuring agent; separating precipitate, calcining | RHONE-POULENC CHIMIE (FR) | 1993-09-21 | — | — | US | disclosed |
| US-4620941-A | CHROMOGEN, DEVELOPER, DESENSITIZER | SAKURA COLOR PRODUCTS CORPORATION (JP) | 1986-11-04 | — | — | US | disclosed |