Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL148999 | 1.00 | MAOB (0.50) | MAOBCYP1A2CNR2ALDH1A1LMNA | |
| SCHEMBL18320470 | 0.85 | MAOB (0.46) | MAOBCYP1A2CNR2ALDH1A1LMNA | |
| (Z)-1,2-Diphenylethene SCHEMBL1892117 | 0.80 | MAOB (0.58) | MAOBALDH1A1NFE2L2CYP19A1MAOA | |
| SCHEMBL7379003 | 0.80 | CYP1A2 (0.48) | MAOBCYP1A2CNR2ALDH1A1LMNA | |
| SCHEMBL3862905 | 0.80 | CYP1A2 (0.48) | MAOBCYP1A2CNR2ALDH1A1LMNA | |
| SCHEMBL3424706 | 0.80 | MAOB (0.46) | MAOBCYP1A2CNR2ALDH1A1LMNA | |
| SCHEMBL7379006 | 0.80 | CYP1A2 (0.48) | MAOBCYP1A2CNR2ALDH1A1LMNA | |
| SCHEMBL13420202 | 0.80 | CYP1A2 (0.48) | MAOBCYP1A2CNR2ALDH1A1LMNA | |
| SCHEMBL10574618 | 0.80 | MAOB (0.46) | MAOBCYP1A2LMNAMAPK1TRPA1 | |
| SCHEMBL5165697 | 0.80 | MAOB (0.46) | MAOBCYP1A2LMNAMAPK1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1231558-C | Alignment layer material for liquid crystal display and method for manufacturing the same | CHANGXING CHEMICAL INDUSTRY CO (CN) | 2005-12-14 | — | — | CN | claimed |
| CN-1504538-A | Alignment layer material for liquid crystal display and method for manufacturing the same | 长兴化学工业股份有限公司 | 2004-06-16 | — | — | CN | claimed |
| CN-1504537-A | Alignment layer material for liquid crystal display and method for manufacturing the same | 长兴化学工业股份有限公司 | 2004-06-16 | — | — | CN | claimed |
| CN-102762541-B | Diaza derivatives as modulators of chemokine receptors | HOFFMAN-LA ROCHE LTD. (CH) | 2016-03-16 | — | — | CN | disclosed |
| CN-103396403-B | Pesticidal compound | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-09 | — | — | CN | disclosed |
| US-20070225269-A1 | Use of (3-(1-(3-Phenyl-Propenyl)-Piperidin-4-Yl)-2,3-Dihydro-Indol-1-Yl)-(Pyridin-4-Yl)-Methanonone Derivatives and Related Compounds as Insecticides | SYNGENTA CROP PROTECTION, INC. | 2007-09-27 | — | — | US | disclosed |
| CN-1231558-C | Alignment layer material for liquid crystal display and method for manufacturing the same | CHANGXING CHEMICAL INDUSTRY CO (CN) | 2005-12-14 | — | — | CN | disclosed |
| CN-1504537-A | Alignment layer material for liquid crystal display and method for manufacturing the same | 长兴化学工业股份有限公司 | 2004-06-16 | — | — | CN | disclosed |
| CN-1504538-A | Alignment layer material for liquid crystal display and method for manufacturing the same | 长兴化学工业股份有限公司 | 2004-06-16 | — | — | CN | disclosed |
| CN-1128797-C | Farnesyl transferase inhibiting 1,8-annelated quinolinone derivs. substd. with N- or C-linked imidazoles | JANSSEN PHARMACEUTICA NV (BE) | 2003-11-26 | — | — | CN | disclosed |
| CN-1249753-A | N-or C-bonded imidazole-substituted 1, 8-fused quinolinone derivatives inhibiting Farnesyl transferase | JANSSEN PHARMACEUTICA NV (BE) | 2000-04-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225269-A1 | Use of (3-(1-(3-Phenyl-Propenyl)-Piperidin-4-Yl)-2,3-Dihydro-Indol-1-Yl)-(Pyridin-4-Yl)-Methanonone Derivatives and Related Compounds as Insecticides | CHRM1, NPY1R, MRM1 | MAOB 1889/4885CYP1A2 448/4885CNR2 383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.