Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.52 |
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5442471 | 0.90 | DPP4 (0.50) | DPP4DPP9DPP8 | |
| SCHEMBL5739223 | 0.88 | DPP4 (0.44) | DPP4DPP9DPP8HDAC1 | |
| SCHEMBL4113112 | 0.88 | DPP4 (0.66) | DPP4DPP9DPP8 | |
| SCHEMBL5449916 | 0.87 | DPP4 (0.53) | DPP4DPP9DPP8ALOX5ALOX5AP | |
| Hydrochloric Acid SCHEMBL5456188 | 0.84 | DPP4 (0.73) | DPP4DPP9DPP8 | |
| SCHEMBL5451905 | 0.82 | DPP4 (0.48) | DPP4DPP9DPP8 | |
| SCHEMBL5454715 | 0.81 | DPP4 (0.47) | DPP4DPP9DPP8 | |
| SCHEMBL4112465 | 0.81 | DPP4 (0.68) | DPP4DPP9DPP8HDAC1 | |
| SCHEMBL5452995 | 0.80 | DPP4 (0.48) | DPP4DPP9DPP8 | |
| SCHEMBL5444823 | 0.80 | DPP4 (0.44) | DPP4DPP9DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037807-A1 | Pyridine compounds as inhibitors of dipeptidyl peptidase IV | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037807-A1 | Pyridine compounds as inhibitors of dipeptidyl peptidase IV | DPP4, DPP3, PEPD | DPP4 1/4885DPP9 5/4885DPP8 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.