Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.68 |
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.68 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4113112 | 0.90 | DPP4 (0.66) | DPP4DPP9DPP8PTGDR2KMT2A | |
| SCHEMBL4117782 | 0.85 | DPP4 (0.49) | DPP4DPP9DPP8 | |
| SCHEMBL5240240 | 0.85 | DPP4 (0.48) | DPP4DPP9DPP8 | |
| SCHEMBL4118538 | 0.84 | DPP4 (0.55) | DPP4DPP9DPP8 | |
| SCHEMBL4105584 | 0.81 | DPP4 (0.63) | DPP4DPP9DPP8KMT2A | |
| SCHEMBL4112626 | 0.81 | DPP4 (1.00) | DPP4DPP9DPP8 | |
| SCHEMBL5456061 | 0.81 | DPP4 (0.66) | DPP4DPP9DPP8 | |
| Hydrochloric Acid SCHEMBL4112752 | 0.81 | DPP4 (0.98) | DPP4DPP9DPP8 | |
| SCHEMBL5455449 | 0.81 | DPP4 (0.52) | DPP4DPP9DPP8HDAC1 | |
| SCHEMBL5449935 | 0.79 | DPP4 (0.55) | DPP4DPP9DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088419-A1 | PYRIDYL ACETIC ACID COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-02 | — | — | US | disclosed |
| EP-1851202-A1 | PYRIDYL ACETIC ACID COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2007-11-07 | — | — | EP | disclosed |
| WO-2006090915-A1 | PYRIDYL ACETIC ACID COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088419-A1 | PYRIDYL ACETIC ACID COMPOUNDS | DPP4, GPR119, DPP3 | DPP4 1/4885DPP9 11/4885DPP8 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.