Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 4/20 | 0.43 |
| ▸ | HTR2C | P28335 | 5/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27627949 | 0.80 | HTR2C (0.43) | PBRM1HTR2CHTR2AHTR2BDDB1 | |
| SCHEMBL2343869 | 0.74 | CACNB4 (0.39) | PBRM1HTR2CHTR2AHTR2BDAO | |
| SCHEMBL6870977 | 0.70 | TTR (0.33) | — | |
| SCHEMBL2346396 | 0.69 | KMT2A (0.46) | HTR2CHTR2BALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL2341298 | 0.68 | MAPT (0.42) | PBRM1HTR2BDDB1CRBNTNKS2 | |
| SCHEMBL2346045 | 0.68 | CACNA1F (0.38) | HTR2CHTR2BALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11686278 | 0.67 | DDB1 (0.44) | PBRM1HTR2CHTR2AHTR2BDDB1 | |
| SCHEMBL5814880 | 0.66 | IDO1 (0.58) | HTR2CDDB1CRBNALDH1A1 | |
| SCHEMBL9802951 | 0.65 | DDB1 (0.49) | PBRM1HTR2CHTR2AHTR2BDDB1 | |
| SCHEMBL29875704 | 0.64 | HTR2C (0.44) | PBRM1HTR2CHTR2AHTR2BTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130187095-A1 | THERMOSETTING ADHESIVE COMPOSITIONS | DESIGNER MOLECULES, INC. (US) | 2013-07-25 | — | — | US | disclosed |
| US-8378017-B2 | Thermosetting adhesive compositions | DESIGNER MOLECULES, INC. (US) | 2013-02-19 | — | — | US | disclosed |
| US-20070155869-A1 | Mono-functional monomers and methods for use thereof | DESIGNER MOLECULES, INC. | 2007-07-05 | — | — | US | disclosed |