Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 9/20 | 0.58 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.54 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2529914 | 0.86 | DDB1 (0.71) | IDO1DDB1CRBNLMNAKDM4E | |
| SCHEMBL9387969 | 0.73 | IDO1 (1.00) | IDO1DDB1CRBNLMNAHSD17B10 | |
| SCHEMBL4429629 | 0.73 | IDO1 (0.58) | IDO1LMNAALDH1A1TP53CYP19A1 | |
| SCHEMBL28972311 | 0.72 | IDO1 (0.61) | IDO1LMNAALDH1A1TP53 | |
| SCHEMBL30325218 | 0.72 | IDO1 (0.61) | IDO1DDB1CRBNLMNACYP19A1 | |
| SCHEMBL6918058 | 0.72 | IDO1 (0.61) | IDO1DDB1CRBNLMNAALDH1A1 | |
| SCHEMBL5323542 | 0.72 | IDO1 (0.61) | IDO1LMNAALDH1A1 | |
| SCHEMBL9818019 | 0.72 | IDO1 (0.61) | IDO1DDB1CRBNLMNAALDH1A1 | |
| SCHEMBL29011873 | 0.72 | IDO1 (0.60) | IDO1DDB1CRBNLMNACYP19A1 | |
| Bromide SCHEMBL28839335 | 0.72 | IDO1 (0.97) | IDO1DDB1CRBNLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006122035-A2 | METHOD FOR TREATING CENTRAL PAIN SYNDROME OR FOR INDUCING CENTRALLY GENERATED PAIN IN AN ANIMAL MODEL | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2006-11-16 | — | — | WO | disclosed |