Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.78 |
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | BLM | P54132 | 1/20 | 0.72 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | MMP1 | P03956 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5455524 | 1.00 | EGFR (0.79) | EGFRKMT2AMEN1LMNATDP1 | |
| SCHEMBL4971304 | 0.84 | KMT2A (0.81) | EGFRKMT2AMEN1LMNATDP1 | |
| SCHEMBL4971301 | 0.84 | KMT2A (0.81) | EGFRKMT2AMEN1LMNATDP1 | |
| SCHEMBL25222060 | 0.83 | EGFR (0.90) | EGFRKMT2AMEN1LMNAPOLB | |
| SCHEMBL5446943 | 0.82 | KMT2A (0.74) | KMT2AMEN1LMNATDP1POLB | |
| SCHEMBL5446938 | 0.82 | KMT2A (0.74) | KMT2AMEN1LMNATDP1POLB | |
| SCHEMBL7814633 | 0.81 | RAB9A (0.81) | KMT2AMEN1LMNATDP1POLB | |
| SCHEMBL7814630 | 0.81 | RAB9A (0.81) | KMT2AMEN1LMNATDP1POLB | |
| SCHEMBL14096628 | 0.80 | MAPT (0.78) | KMT2AMEN1LMNATDP1POLB | |
| SCHEMBL14095995 | 0.80 | RAB9A (0.67) | KMT2AMEN1LMNATDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |