Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 11/20 | 0.74 |
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5446246 | 0.89 | FLT3 (0.73) | FLT3RAB9AALDH1A1HPGDALOX15 | |
| SCHEMBL5455906 | 0.89 | FLT3 (0.74) | FLT3RAB9AALDH1A1HPGDALOX15 | |
| SCHEMBL5456151 | 0.87 | FLT3 (0.62) | FLT3RAB9AALDH1A1HPGDALOX15 | |
| SCHEMBL5460961 | 0.86 | FLT3 (0.55) | FLT3RAB9AALDH1A1HPGDALOX15 | |
| SCHEMBL5455531 | 0.83 | FLT3 (0.61) | FLT3RAB9AALDH1A1HPGDALOX15 | |
| SCHEMBL5462791 | 0.80 | FLT3 (0.72) | FLT3ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL5455065 | 0.80 | MEN1 (0.79) | FLT3RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL5450860 | 0.80 | MEN1 (0.78) | FLT3RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL5458235 | 0.80 | FLT3 (0.55) | FLT3RAB9AALDH1A1HPGDALOX15 | |
| SCHEMBL5458963 | 0.79 | FLT3 (0.71) | FLT3RAB9AALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | claimed |
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | TBCA, PARK7, NFATC1 | FLT3 3509/4885RAB9A 948/4885ALDH1A1 1153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.